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Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth.
Efstathiou A, Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Subota I, Aicher S, Mikros E, Bastin P, Skaltsounis AL, Soteriadou K, Smirlis D. Efstathiou A, et al. Among authors: myrianthopoulos v. Antimicrob Agents Chemother. 2019 May 24;63(6):e02065-18. doi: 10.1128/AAC.02065-18. Print 2019 Jun. Antimicrob Agents Chemother. 2019. PMID: 30910902 Free PMC article.
Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors.
Fantel AM, Myrianthopoulos V, Georgoulis A, Lougiakis N, Zantza I, Lamprinidis G, Augsburger F, Marakos P, Vorgias CE, Szabo C, Pouli N, Papapetropoulos A, Mikros E. Fantel AM, et al. Among authors: myrianthopoulos v. Molecules. 2020 Aug 16;25(16):3739. doi: 10.3390/molecules25163739. Molecules. 2020. PMID: 32824311 Free PMC article.
An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3.
Efstathiou A, Gaboriaud-Kolar N, Smirlis D, Myrianthopoulos V, Vougogiannopoulou K, Alexandratos A, Kritsanida M, Mikros E, Soteriadou K, Skaltsounis AL. Efstathiou A, et al. Among authors: myrianthopoulos v. Parasit Vectors. 2014 May 20;7:234. doi: 10.1186/1756-3305-7-234. Parasit Vectors. 2014. PMID: 24886176 Free PMC article.
Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
Myrianthopoulos V, Gaboriaud-Kolar N, Tallant C, Hall ML, Grigoriou S, Brownlee PM, Fedorov O, Rogers C, Heidenreich D, Wanior M, Drosos N, Mexia N, Savitsky P, Bagratuni T, Kastritis E, Terpos E, Filippakopoulos P, Müller S, Skaltsounis AL, Downs JA, Knapp S, Mikros E. Myrianthopoulos V, et al. J Med Chem. 2016 Oct 13;59(19):8787-8803. doi: 10.1021/acs.jmedchem.6b00355. Epub 2016 Sep 27. J Med Chem. 2016. PMID: 27617704 Free PMC article.
Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.
Myrianthopoulos V, Kritsanida M, Gaboriaud-Kolar N, Magiatis P, Ferandin Y, Durieu E, Lozach O, Cappel D, Soundararajan M, Filippakopoulos P, Sherman W, Knapp S, Meijer L, Mikros E, Skaltsounis AL. Myrianthopoulos V, et al. ACS Med Chem Lett. 2013 Jan 10;4(1):22-26. doi: 10.1021/ml300207a. Epub 2012 Nov 1. ACS Med Chem Lett. 2013. PMID: 23336033 Free PMC article.
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