Myles T - Search Results

1

Thrombin cleavage of osteopontin initiates osteopontin's tumor-promoting activity.

Peraramelli S, Zhou Q, Zhou Q, Wanko B, Zhao L, Nishimura T, Leung TH, Mizuno S, Ito M, Myles T, Stulnig TM, Morser J, Leung LLK. Peraramelli S, et al. Among authors: myles t. J Thromb Haemost. 2022 May;20(5):1256-1270. doi: 10.1111/jth.15663. Epub 2022 Feb 16. J Thromb Haemost. 2022. PMID: 35108449 Free PMC article.

2

An extensive interaction interface between thrombin and factor V is required for factor V activation.

Myles T, Yun TH, Hall SW, Leung LL. Myles T, et al. J Biol Chem. 2001 Jul 6;276(27):25143-9. doi: 10.1074/jbc.M011324200. Epub 2001 Apr 18. J Biol Chem. 2001. PMID: 11312264 Free article.

3

Structural requirements for the activation of human factor VIII by thrombin.

Myles T, Yun TH, Leung LL. Myles T, et al. Blood. 2002 Oct 15;100(8):2820-6. doi: 10.1182/blood-2002-03-0843. Blood. 2002. PMID: 12351390 Free article.

4

Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ib alpha with thrombin anion-binding exosites I and II, respectively.

Yun TH, Baglia FA, Myles T, Navaneetham D, López JA, Walsh PN, Leung LL. Yun TH, et al. Among authors: myles t. J Biol Chem. 2003 Nov 28;278(48):48112-9. doi: 10.1074/jbc.M306925200. Epub 2003 Sep 10. J Biol Chem. 2003. PMID: 12968031 Free article.

5

Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation.

Myles T, Nishimura T, Yun TH, Nagashima M, Morser J, Patterson AJ, Pearl RG, Leung LL. Myles T, et al. J Biol Chem. 2003 Dec 19;278(51):51059-67. doi: 10.1074/jbc.M306977200. Epub 2003 Oct 2. J Biol Chem. 2003. PMID: 14525995 Free article.

6

Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.

Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Carter WJ, et al. Among authors: myles t. J Biol Chem. 2004 Jun 18;279(25):26387-94. doi: 10.1074/jbc.M402364200. Epub 2004 Apr 9. J Biol Chem. 2004. PMID: 15075325 Free article.

7

Molecular mapping of the thrombin-heparin cofactor II complex.

Fortenberry YM, Whinna HC, Gentry HR, Myles T, Leung LL, Church FC. Fortenberry YM, et al. Among authors: myles t. J Biol Chem. 2004 Oct 8;279(41):43237-44. doi: 10.1074/jbc.M406716200. Epub 2004 Aug 2. J Biol Chem. 2004. PMID: 15292227 Free article.

8

Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain.

Nogami K, Zhou Q, Myles T, Leung LL, Wakabayashi H, Fay PJ. Nogami K, et al. Among authors: myles t. J Biol Chem. 2005 May 6;280(18):18476-87. doi: 10.1074/jbc.M412778200. Epub 2005 Mar 3. J Biol Chem. 2005. PMID: 15746105 Free article.

9

Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.

Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL. Nishimura T, et al. Among authors: myles t. Blood. 2007 Mar 1;109(5):1992-7. doi: 10.1182/blood-2006-03-012567. Epub 2006 Nov 14. Blood. 2007. PMID: 17105819 Free PMC article.

10

Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin.

Fortenberry YM, Whinna HC, Cooper ST, Myles T, Leung LL, Church FC. Fortenberry YM, et al. Among authors: myles t. J Thromb Haemost. 2007 Jul;5(7):1486-92. doi: 10.1111/j.1538-7836.2007.02574.x. J Thromb Haemost. 2007. PMID: 17635698 Free article.

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