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Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain.
Nong J, Glassman PM, Myerson JW, Zuluaga-Ramirez V, Rodriguez-Garcia A, Mukalel A, Omo-Lamai S, Walsh LR, Zamora ME, Gong X, Wang Z, Bhamidipati K, Kiseleva RY, Villa CH, Greineder CF, Kasner SE, Weissman D, Mitchell MJ, Muro S, Persidsky Y, Brenner JS, Muzykantov VR, Marcos-Contreras OA. Nong J, et al. Among authors: myerson jw. ACS Nano. 2023 Jul 25;17(14):13121-13136. doi: 10.1021/acsnano.2c08275. Epub 2023 Jul 11. ACS Nano. 2023. PMID: 37432926 Free article.
Systems approaches to design of targeted therapeutic delivery.
Myerson JW, Brenner JS, Greineder CF, Muzykantov VR. Myerson JW, et al. Wiley Interdiscip Rev Syst Biol Med. 2015 Sep-Oct;7(5):253-65. doi: 10.1002/wsbm.1304. Epub 2015 May 6. Wiley Interdiscip Rev Syst Biol Med. 2015. PMID: 25946066 Free PMC article. Review.
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions.
Brenner JS, Bhamidipati K, Glassman PM, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa CH, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Brenner JS, et al. Among authors: myerson jw. Nanomedicine. 2017 May;13(4):1495-1506. doi: 10.1016/j.nano.2016.12.019. Epub 2017 Jan 5. Nanomedicine. 2017. PMID: 28065731 Free PMC article.
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude.
Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, Shuvaeva T, Khoshnejad M, Johnston I, Gregory JV, Lahann J, Wang T, Cantu E, Armstead WM, Mitragotri S, Muzykantov V. Brenner JS, et al. Among authors: myerson jw. Nat Commun. 2018 Jul 11;9(1):2684. doi: 10.1038/s41467-018-05079-7. Nat Commun. 2018. PMID: 29992966 Free PMC article.
Unintended effects of drug carriers: Big issues of small particles.
Parhiz H, Khoshnejad M, Myerson JW, Hood E, Patel PN, Brenner JS, Muzykantov VR. Parhiz H, et al. Among authors: myerson jw. Adv Drug Deliv Rev. 2018 May;130:90-112. doi: 10.1016/j.addr.2018.06.023. Epub 2018 Jul 3. Adv Drug Deliv Rev. 2018. PMID: 30149885 Free PMC article. Review.
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain.
Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. Among authors: myerson jw. J Control Release. 2019 May 10;301:54-61. doi: 10.1016/j.jconrel.2019.03.008. Epub 2019 Mar 11. J Control Release. 2019. PMID: 30871995 Free PMC article.
46 results