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Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput.
Kennedy PH, Alborzian Deh Sheikh A, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer CG, Alarcón S, Newby GA, Myers SA. Kennedy PH, et al. Among authors: myers sa. Nat Methods. 2024 Apr 29. doi: 10.1038/s41592-024-02256-z. Online ahead of print. Nat Methods. 2024. PMID: 38684783
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide.
Sepulveda H, Li X, Yue X, Carlos Angel J, Arteaga-Vazquez LJ, Brown C, Brunelli M, Jansz N, Puddu F, Scotcher J, Creed P, Kennedy P, Manriquez C, Myers SA, Crawford R, Faulkner GJ, Rao A. Sepulveda H, et al. Among authors: myers sa. bioRxiv [Preprint]. 2024 Jan 31:2024.01.31.578097. doi: 10.1101/2024.01.31.578097. bioRxiv. 2024. PMID: 38352366 Free PMC article. Preprint.
Peripheral artery disease causes consistent gait irregularities regardless of the location of leg claudication pain.
Rahman H, Leutzinger T, Hassan M, Schieber M, Koutakis P, Fuglestad MA, DeSpiegelaere H, Longo GM, Malcolm P, Johanning JM, Casale GP, Pipinos II, Myers SA. Rahman H, et al. Among authors: myers sa. Ann Phys Rehabil Med. 2024 Apr;67(3):101793. doi: 10.1016/j.rehab.2023.101793. Epub 2023 Dec 20. Ann Phys Rehabil Med. 2024. PMID: 38118246 Free article. Clinical Trial.
Proteome-wide base editor screens to assess phosphorylation site functionality in high-throughput.
Kennedy PH, Deh Sheikh AA, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer C, Alarcón S, Newby G, Myers SA. Kennedy PH, et al. Among authors: myers sa. bioRxiv [Preprint]. 2023 Nov 14:2023.11.11.566649. doi: 10.1101/2023.11.11.566649. bioRxiv. 2023. PMID: 38014346 Free PMC article. Updated. Preprint.
240 results