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Page 1
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Svensson MND, et al. Among authors: mydel p. Sci Adv. 2020 Jun 26;6(26):eaba4353. doi: 10.1126/sciadv.aba4353. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637608 Free PMC article.
Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice.
Stanford SM, Svensson MN, Sacchetti C, Pilo CA, Wu DJ, Kiosses WB, Hellvard A, Bergum B, Muench GR, Elly C, Liu YC, den Hertog J, Elson A, Sap J, Mydel P, Boyle DL, Corr M, Firestein GS, Bottini N. Stanford SM, et al. Among authors: mydel p. Arthritis Rheumatol. 2016 Feb;68(2):359-69. doi: 10.1002/art.39442. Arthritis Rheumatol. 2016. PMID: 26414708 Free PMC article.
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Svensson MN, Doody KM, Schmiedel BJ, Bhattacharyya S, Panwar B, Wiede F, Yang S, Santelli E, Wu DJ, Sacchetti C, Gujar R, Seumois G, Kiosses WB, Aubry I, Kim G, Mydel P, Sakaguchi S, Kronenberg M, Tiganis T, Tremblay ML, Ay F, Vijayanand P, Bottini N. Svensson MN, et al. Among authors: mydel p. J Clin Invest. 2019 Mar 1;129(3):1193-1210. doi: 10.1172/JCI123267. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30620725 Free PMC article.
Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis.
Hellvard A, Zeitlmann L, Heiser U, Kehlen A, Niestroj A, Demuth HU, Koziel J, Delaleu N, Jan Potempa, Mydel P. Hellvard A, et al. Among authors: mydel p. Sci Rep. 2016 Aug 11;6:31441. doi: 10.1038/srep31441. Sci Rep. 2016. PMID: 27511630 Free PMC article.
Peptidylarginine deiminase 4 (PAD4) activity in early rheumatoid arthritis.
Jonsson MK, Kantyka T, Falkowski K, Aliko A, Aga AB, Lillegraven S, Sexton J, Fevang BT, Mydel P, Haavardsholm EA. Jonsson MK, et al. Among authors: mydel p. Scand J Rheumatol. 2020 Mar;49(2):87-95. doi: 10.1080/03009742.2019.1641216. Epub 2019 Sep 23. Scand J Rheumatol. 2020. PMID: 31544586
Glutaminyl cyclases as novel targets for the treatment of septic arthritis.
Hellvard A, Maresz K, Schilling S, Graubner S, Heiser U, Jonsson R, Cynis H, Demuth HU, Potempa J, Mydel P. Hellvard A, et al. Among authors: mydel p. J Infect Dis. 2013 Mar 1;207(5):768-77. doi: 10.1093/infdis/jis729. Epub 2012 Nov 29. J Infect Dis. 2013. PMID: 23204180 Free PMC article.
Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.
Dominy SS, Lynch C, Ermini F, Benedyk M, Marczyk A, Konradi A, Nguyen M, Haditsch U, Raha D, Griffin C, Holsinger LJ, Arastu-Kapur S, Kaba S, Lee A, Ryder MI, Potempa B, Mydel P, Hellvard A, Adamowicz K, Hasturk H, Walker GD, Reynolds EC, Faull RLM, Curtis MA, Dragunow M, Potempa J. Dominy SS, et al. Among authors: mydel p. Sci Adv. 2019 Jan 23;5(1):eaau3333. doi: 10.1126/sciadv.aau3333. eCollection 2019 Jan. Sci Adv. 2019. PMID: 30746447 Free PMC article.
51 results