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Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells.
Mueller J, Schimmer RR, Koch C, Schneiter F, Fullin J, Lysenko V, Pellegrino C, Klemm N, Russkamp N, Myburgh R, Volta L, Theocharides AP, Kurppa KJ, Ebert BL, Schroeder T, Manz MG, Boettcher S. Mueller J, et al. Among authors: myburgh r. EMBO Mol Med. 2024 Mar;16(3):445-474. doi: 10.1038/s44321-024-00024-2. Epub 2024 Feb 14. EMBO Mol Med. 2024. PMID: 38355749 Free PMC article.
Erratum: Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells.
Magnani CF, Myburgh R, Brunn S, Chambovey M, Ponzo M, Volta L, Manfredi F, Pellegrino C, Pascolo S, Miskey C, Sandoval-Villegas N, Ivics Z, Shizuru JA, Neri D, Manz MG. Magnani CF, et al. Among authors: myburgh r. Mol Ther Oncolytics. 2023 Aug 20;30:150. doi: 10.1016/j.omto.2023.08.002. eCollection 2023 Sep 21. Mol Ther Oncolytics. 2023. PMID: 37654971 Free PMC article.
Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells.
Magnani CF, Myburgh R, Brunn S, Chambovey M, Ponzo M, Volta L, Manfredi F, Pellegrino C, Pascolo S, Miskey C, Ivics Z, Shizuru JA, Neri D, Manz MG. Magnani CF, et al. Among authors: myburgh r. Mol Ther Oncolytics. 2023 Jul 19;30:56-71. doi: 10.1016/j.omto.2023.07.003. eCollection 2023 Sep 21. Mol Ther Oncolytics. 2023. PMID: 37583386 Free PMC article.
Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia.
El Khawanky N, Hughes A, Yu W, Myburgh R, Matschulla T, Taromi S, Aumann K, Clarson J, Vinnakota JM, Shoumariyeh K, Miething C, Lopez AF, Brown MP, Duyster J, Hein L, Manz MG, Hughes TP, White DL, Yong ASM, Zeiser R. El Khawanky N, et al. Among authors: myburgh r. Nat Commun. 2021 Nov 8;12(1):6436. doi: 10.1038/s41467-021-26683-0. Nat Commun. 2021. PMID: 34750374 Free PMC article.
Publisher Correction: Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.
Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, Vogt PK, Scheuermann J, Neri D. Favalli N, et al. Among authors: myburgh r. Nat Chem. 2021 Jul;13(7):714. doi: 10.1038/s41557-021-00742-x. Nat Chem. 2021. PMID: 34103693 No abstract available.
Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.
Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, Vogt PK, Scheuermann J, Neri D. Favalli N, et al. Among authors: myburgh r. Nat Chem. 2021 Jun;13(6):540-548. doi: 10.1038/s41557-021-00660-y. Epub 2021 Apr 8. Nat Chem. 2021. PMID: 33833446 Free PMC article.
Disruption of CSF-1R signaling inhibits growth of AML with inv(16).
Simonis A, Russkamp NF, Mueller J, Wilk CM, Wildschut MHE, Myburgh R, Wildner-Verhey van Wijk N, Mueller R, Balabanov S, Valk PJM, Theocharides APA, Manz MG. Simonis A, et al. Among authors: myburgh r. Blood Adv. 2021 Mar 9;5(5):1273-1277. doi: 10.1182/bloodadvances.2020003125. Blood Adv. 2021. PMID: 33651098 Free PMC article.
27 results