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Structural Requirements for CNS Active Opioid Glycopeptides.
Lefever M, Li Y, Anglin B, Muthu D, Giuvelis D, Lowery JJ, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Lefever M, et al. Among authors: muthu d. J Med Chem. 2015 Aug 13;58(15):5728-41. doi: 10.1021/acs.jmedchem.5b00014. Epub 2015 Jul 23. J Med Chem. 2015. PMID: 26125201
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord.
Lee YS, Muthu D, Hall SM, Ramos-Colon C, Rankin D, Hu J, Sandweiss AJ, De Felice M, Xie JY, Vanderah TW, Porreca F, Lai J, Hruby VJ. Lee YS, et al. Among authors: muthu d. J Am Chem Soc. 2014 May 7;136(18):6608-16. doi: 10.1021/ja501677q. Epub 2014 Apr 29. J Am Chem Soc. 2014. PMID: 24742335 Free PMC article.
NMR studies of the dynamics of high-spin nitrophorins: comparative studies of NP4 and NP2 at close to physiological pH.
Berry RE, Muthu D, Yang F, Walker FA. Berry RE, et al. Among authors: muthu d. Biochemistry. 2015 Jan 20;54(2):221-39. doi: 10.1021/bi501305a. Epub 2014 Dec 24. Biochemistry. 2015. PMID: 25486224 Free PMC article.
In comparison, NP2-OH2 shows much less dynamics, albeit somewhat more than that of the previously reported NP2-NO complex [Muthu, D., Berry, R. E., Zhang, H., and Walker, F. A. (2013) Biochemistry 52, 7910-7925]. ...
In comparison, NP2-OH2 shows much less dynamics, albeit somewhat more than that of the previously reported NP2-NO complex [Muthu, …
34 results