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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1969 3
1970 1
1971 1
1972 1
1973 6
1974 5
1975 12
1976 12
1977 8
1978 17
1979 12
1980 18
1981 23
1982 30
1983 30
1984 55
1985 57
1986 58
1987 82
1988 124
1989 131
1990 158
1991 186
1992 228
1993 253
1994 245
1995 264
1996 274
1997 291
1998 362
1999 330
2000 337
2001 360
2002 339
2003 348
2004 410
2005 430
2006 416
2007 414
2008 366
2009 388
2010 415
2011 388
2012 493
2013 506
2014 470
2015 517
2016 494
2017 506
2018 510
2019 608
2020 664
2021 703
2022 664
2023 641
2024 268

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13,708 results

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Page 1
Showing results for mutate gc
Search for Mutati GC instead (3 results)
Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria.
Teng W, Liao B, Chen M, Shu W. Teng W, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0214522. doi: 10.1128/spectrum.02145-22. Epub 2022 Dec 13. Microbiol Spectr. 2023. PMID: 36511682 Free PMC article.
Such variation of the genomic GC can be well explained by DNA replication and repair (DRR), in which multiple pathways correlate with the genomic GC. ...Our findings support that the mutational biases resulting from these legacies of ancient adaptation have c …
Such variation of the genomic GC can be well explained by DNA replication and repair (DRR), in which multiple pathways correlate with …
GC content of plant genes is linked to past gene duplications.
Bowers JE, Tang H, Burke JM, Paterson AH. Bowers JE, et al. PLoS One. 2022 Jan 13;17(1):e0261748. doi: 10.1371/journal.pone.0261748. eCollection 2022. PLoS One. 2022. PMID: 35025913 Free PMC article.
Two mutation types can account for biased GC content, mutation of methylated C to T and gene conversion from A to G. ...We propose a "biased gene duplication / biased mutation" (BDBM) model that may explain the origin and trajectory of the observed lin …
Two mutation types can account for biased GC content, mutation of methylated C to T and gene conversion from A to G. .. …
Microsatellite instability: an update.
Yamamoto H, Imai K. Yamamoto H, et al. Arch Toxicol. 2015 Jun;89(6):899-921. doi: 10.1007/s00204-015-1474-0. Epub 2015 Feb 22. Arch Toxicol. 2015. PMID: 25701956 Review.
MSI is characterized by length alterations within simple repeated sequences that are called microsatellites. Lynch syndrome is primarily caused by mutations in the MMR genes, mainly MLH1 and MSH2, and less frequently in MSH6, and rarely PMS2, and large genomic rearrangemen …
MSI is characterized by length alterations within simple repeated sequences that are called microsatellites. Lynch syndrome is primarily cau …
Gene mutations in gastric cancer: a review of recent next-generation sequencing studies.
Lin Y, Wu Z, Guo W, Li J. Lin Y, et al. Tumour Biol. 2015 Sep;36(10):7385-94. doi: 10.1007/s13277-015-4002-1. Epub 2015 Sep 12. Tumour Biol. 2015. PMID: 26364057 Review.
The development of next-generation sequencing (NGS) provides a high-throughput and systematic method to identify all genetic alterations in the cancer genome, especially in the field of mutation detection. NGS studies in GC have discovered some novel driver mutat …
The development of next-generation sequencing (NGS) provides a high-throughput and systematic method to identify all genetic alterations in …
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer.
Cheng Y, Bu D, Zhang Q, Sun R, Lyle S, Zhao G, Dong L, Li H, Zhao Y, Yu J, Hao X. Cheng Y, et al. J Adv Res. 2023 Sep;51:121-134. doi: 10.1016/j.jare.2022.10.019. Epub 2022 Nov 10. J Adv Res. 2023. PMID: 36351537 Free PMC article.
However, the prognostic significance and subtype of TMB in GC is not fully understood. OBJECTIVES: This study aims to evaluate the prognostic value of TMB in Chinese GC and further classify TMB-high GC (GC(TMB-H)) patients combing with mutational …
However, the prognostic significance and subtype of TMB in GC is not fully understood. OBJECTIVES: This study aims to evaluate the pr …
Mutation bias and GC content shape antimutator invasions.
Couce A, Tenaillon O. Couce A, et al. Nat Commun. 2019 Jul 15;10(1):3114. doi: 10.1038/s41467-019-11217-6. Nat Commun. 2019. PMID: 31308380 Free PMC article.
While antimutator invasions have been documented experimentally, important discrepancies among studies remain currently unexplained. Here we show that a largely neglected factor, the mutational idiosyncrasy displayed by different mutators, can play a major role in t …
While antimutator invasions have been documented experimentally, important discrepancies among studies remain currently unexplained. Here we …
Mutational landscape of receptor guanylyl cyclase C: Functional analysis and disease-related mutations.
Bose A, Banerjee S, Visweswariah SS. Bose A, et al. IUBMB Life. 2020 Jun;72(6):1145-1159. doi: 10.1002/iub.2283. Epub 2020 Apr 15. IUBMB Life. 2020. PMID: 32293781 Free PMC article. Review.
We also summarize the available information on mutations in GC-C that have been reported in humans and contribute to severe gastrointestinal abnormalities. Since GC-C is also expressed in extra-intestinal tissues, it is likely that mutations thus far r …
We also summarize the available information on mutations in GC-C that have been reported in humans and contribute to severe ga …
Review of published 467 achondroplasia patients: clinical and mutational spectrum.
Zhang X, Jiang S, Zhang R, Guo S, Sheng Q, Wang K, Shan Y, Liao L, Dong J. Zhang X, et al. Orphanet J Rare Dis. 2024 Jan 27;19(1):29. doi: 10.1186/s13023-024-03031-1. Orphanet J Rare Dis. 2024. PMID: 38281003 Free PMC article. Review.
This study aims to analyse the clinical characteristics and gene mutations of ACH to accurately determine whether a patient has ACH and to raise public awareness of the disease. ...CONCLUSION: ACH was caused by FGFR3 gene mutation, and c.1138G > A was the most co …
This study aims to analyse the clinical characteristics and gene mutations of ACH to accurately determine whether a patient has ACH a …
DDX24 Mutation Alters NPM1 Phase Behavior and Disrupts Nucleolar Homeostasis in Vascular Malformations.
Zhang H, Chen Q, Zhang Q, Gan H, Li H, Chen S, Shan H, Pang P, He H. Zhang H, et al. Int J Biol Sci. 2023 Aug 6;19(13):4123-4138. doi: 10.7150/ijbs.84097. eCollection 2023. Int J Biol Sci. 2023. PMID: 37705750 Free PMC article.
Furthermore, DDX24 was directly associated with NPM1 to regulate its phase behavior as a client in the nucleolar granular component (GC). Functionally, we showed that DDX24 was essential in maintaining nucleolar homeostasis of ECs and that either mutation or knockdo …
Furthermore, DDX24 was directly associated with NPM1 to regulate its phase behavior as a client in the nucleolar granular component (GC …
In-depth investigation of the point mutation pattern of HIV-1.
Sun N, Yau SS. Sun N, et al. Front Cell Infect Microbiol. 2022 Nov 15;12:1033481. doi: 10.3389/fcimb.2022.1033481. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36457853 Free PMC article.
Therefore, it is of great significance to understand how mutations drive the virulence of HIV. Based on the 11897 reliable genomes of HIV-1 retrieved from HIV sequence Database, we analyze the 12 types of point mutation (A>C, A>G, A>T, C>A, C>G, C> …
Therefore, it is of great significance to understand how mutations drive the virulence of HIV. Based on the 11897 reliable genomes of …
13,708 results
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