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Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias.
Pabel S, Mustroph J, Stehle T, Lebek S, Dybkova N, Keyser A, Rupprecht L, Wagner S, Neef S, Maier LS, Sossalla S. Pabel S, et al. Among authors: mustroph j. Europace. 2020 Jul 1;22(7):1111-1118. doi: 10.1093/europace/euaa079. Europace. 2020. PMID: 32413138
CaMKII regulation of cardiac K channels.
Mustroph J, Maier LS, Wagner S. Mustroph J, et al. Front Pharmacol. 2014 Feb 21;5:20. doi: 10.3389/fphar.2014.00020. eCollection 2014. Front Pharmacol. 2014. PMID: 24600393 Free PMC article. Review.
CaMKII as a target for arrhythmia suppression.
Mustroph J, Neef S, Maier LS. Mustroph J, et al. Pharmacol Ther. 2017 Aug;176:22-31. doi: 10.1016/j.pharmthera.2016.10.006. Epub 2016 Oct 11. Pharmacol Ther. 2017. PMID: 27742568 Review.
The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity.
Lebek S, Plößl A, Baier M, Mustroph J, Tarnowski D, Lücht CM, Schopka S, Flörchinger B, Schmid C, Zausig Y, Pagratis N, Marchand B, Koltun DO, Hung WK, Ahmadyar S, Belardinelli L, Maier LS, Wagner S. Lebek S, et al. Among authors: mustroph j. J Mol Cell Cardiol. 2018 May;118:159-168. doi: 10.1016/j.yjmcc.2018.03.020. Epub 2018 Mar 31. J Mol Cell Cardiol. 2018. PMID: 29614261
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Empagliflozin directly improves diastolic function in human heart failure.
Pabel S, Wagner S, Bollenberg H, Bengel P, Kovács Á, Schach C, Tirilomis P, Mustroph J, Renner A, Gummert J, Fischer T, Van Linthout S, Tschöpe C, Streckfuss-Bömeke K, Hasenfuss G, Maier LS, Hamdani N, Sossalla S. Pabel S, et al. Among authors: mustroph j. Eur J Heart Fail. 2018 Dec;20(12):1690-1700. doi: 10.1002/ejhf.1328. Epub 2018 Oct 17. Eur J Heart Fail. 2018. PMID: 30328645 Free article.
32 results