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53 results

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Page 1
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice.
Huhtaniemi R, Sipilä P, Junnila A, Oksala R, Knuuttila M, Mehmood A, Aho E, Laajala TD, Aittokallio T, Laiho A, Elo L, Ohlsson C, Thulin MH, Kallio P, Mäkelä S, Mustonen MVJ, Poutanen M. Huhtaniemi R, et al. Among authors: mustonen mvj. iScience. 2022 Apr 25;25(5):104287. doi: 10.1016/j.isci.2022.104287. eCollection 2022 May 20. iScience. 2022. PMID: 35573198 Free PMC article.
Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours.
Bono P, Massard C, Peltola KJ, Azaro A, Italiano A, Kristeleit RS, Curigliano G, Lassen U, Arkenau HT, Hakulinen P, Garratt C, Ikonen T, Mustonen MVJ, Rodon JA. Bono P, et al. Among authors: mustonen mvj. ESMO Open. 2020 Dec;5(6):e001081. doi: 10.1136/esmoopen-2020-001081. ESMO Open. 2020. PMID: 33262202 Free PMC article. Clinical Trial.
Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts.
Huhtaniemi R, Oksala R, Knuuttila M, Mehmood A, Aho E, Laajala TD, Nicorici D, Aittokallio T, Laiho A, Elo L, Ohlsson C, Kallio P, Mäkelä S, Mustonen MVJ, Sipilä P, Poutanen M. Huhtaniemi R, et al. Among authors: mustonen mvj. Am J Pathol. 2018 Dec;188(12):2890-2901. doi: 10.1016/j.ajpath.2018.07.029. Epub 2018 Sep 28. Am J Pathol. 2018. PMID: 30273606 Free article.
ODM-204, a Novel Dual Inhibitor of CYP17A1 and Androgen Receptor: Early Results from Phase I Dose Escalation in Men with Castration-resistant Prostate Cancer.
Peltola KJ, Bono P, Jones RH, Vjaters E, Nykänen P, Vuorela A, Oksala R, Pohjanjousi P, Mustonen MVJ, Fizazi K, Massard C. Peltola KJ, et al. Among authors: mustonen mvj. Eur Urol Focus. 2020 Jan 15;6(1):63-70. doi: 10.1016/j.euf.2018.08.022. Epub 2018 Sep 5. Eur Urol Focus. 2020. PMID: 30194031 Free article. Clinical Trial.
Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1.
Oksala R, Moilanen A, Riikonen R, Rummakko P, Karjalainen A, Passiniemi M, Wohlfahrt G, Taavitsainen P, Malmström C, Ramela M, Metsänkylä HM, Huhtaniemi R, Kallio PJ, Mustonen MV. Oksala R, et al. Among authors: mustonen mv. J Steroid Biochem Mol Biol. 2019 Sep;192:105115. doi: 10.1016/j.jsbmb.2018.02.004. Epub 2018 Feb 10. J Steroid Biochem Mol Biol. 2019. PMID: 29438723 Free article.
Safety and Antitumour Activity of ODM-201 (BAY-1841788) in Castration-resistant, CYP17 Inhibitor-naïve Prostate Cancer: Results from Extended Follow-up of the ARADES Trial.
Fizazi K, Massard C, Bono P, Kataja V, James N, Tammela TL, Joensuu H, Aspegren J, Mustonen M. Fizazi K, et al. Among authors: mustonen m. Eur Urol Focus. 2017 Dec;3(6):606-614. doi: 10.1016/j.euf.2017.01.010. Epub 2017 Feb 27. Eur Urol Focus. 2017. PMID: 28753849 Free article. Clinical Trial.
53 results