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Probing the chemical 'reactome' with high-throughput experimentation data.
Nat Chem. 2024 Apr;16(4):633-643. doi: 10.1038/s41557-023-01393-w. Epub 2024 Jan 2.
Nat Chem. 2024.
PMID: 38168924
Free PMC article.
Kinetic Modeling of API Oxidation: (2) Imipramine Stress Testing.
Wu H, Grinberg Dana A, Ranasinghe DS, Pickard FC 4th, Wood GPF, Zelesky T, Sluggett GW, Mustakis J, Green WH.
Wu H, et al. Among authors: mustakis j.
Mol Pharm. 2022 May 2;19(5):1526-1539. doi: 10.1021/acs.molpharmaceut.2c00043. Epub 2022 Apr 18.
Mol Pharm. 2022.
PMID: 35435696
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Kinetic Modeling of API Oxidation: (1) The AIBN/H2O/CH3OH Radical "Soup".
Grinberg Dana A, Wu H, Ranasinghe DS, Pickard FC 4th, Wood GPF, Zelesky T, Sluggett GW, Mustakis J, Green WH.
Grinberg Dana A, et al. Among authors: mustakis j.
Mol Pharm. 2021 Aug 2;18(8):3037-3049. doi: 10.1021/acs.molpharmaceut.1c00261. Epub 2021 Jul 8.
Mol Pharm. 2021.
PMID: 34236207
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Stereoelectronic Effects in Ligand Design: Enantioselective Rhodium-Catalyzed Hydrogenation of Aliphatic Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib.
Li C, Wan F, Chen Y, Peng H, Tang W, Yu S, McWilliams JC, Mustakis J, Samp L, Maguire RJ.
Li C, et al. Among authors: mustakis j.
Angew Chem Int Ed Engl. 2019 Sep 16;58(38):13573-13583. doi: 10.1002/anie.201908089. Epub 2019 Aug 13.
Angew Chem Int Ed Engl. 2019.
PMID: 31343811
Review.
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Mild and efficient DBU-catalyzed amidation of cyanoacetates.
Price KE, Larrivée-Aboussafy C, Lillie BM, McLaughlin RW, Mustakis J, Hettenbach KW, Hawkins JM, Vaidyanathan R.
Price KE, et al. Among authors: mustakis j.
Org Lett. 2009 May 7;11(9):2003-6. doi: 10.1021/ol900435t.
Org Lett. 2009.
PMID: 19341310
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