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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga ZV, Paloczi J, Miliano C, Donvito G, van Esbroeck ACM, van der Gracht AMF, Kotsogianni I, Park JK, Martella A, van der Wel T, Soethoudt M, Jiang M, Wendel TJ, Janssen APA, Bakker AT, Donovan CM, Castillo LI, Florea BI, Wat J, van den Hurk H, Wittwer M, Grether U, Holmes A, van Boeckel CAA, Hankemeier T, Cravatt BF, Buczynski MW, Hill MN, Pacher P, Lichtman AH, van der Stelt M. Mock ED, et al. Among authors: mustafa m. Nat Chem Biol. 2020 Jun;16(6):667-675. doi: 10.1038/s41589-020-0528-7. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393901 Free PMC article.
HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction.
Poklis JL, Clay DJ, Ignatowska-Jankowska BM, Zanato C, Ross RA, Greig IR, Abdullah RA, Mustafa MA, Lichtman AH, Poklis A. Poklis JL, et al. Among authors: mustafa ma. J Anal Toxicol. 2015 Jun;39(5):353-8. doi: 10.1093/jat/bkv015. Epub 2015 Mar 3. J Anal Toxicol. 2015. PMID: 25737338 Free PMC article.
The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice.
Wilkerson JL, Ghosh S, Mustafa M, Abdullah RA, Niphakis MJ, Cabrera R, Maldonado RL, Cravatt BF, Lichtman AH. Wilkerson JL, et al. Among authors: mustafa m. Neuropharmacology. 2017 Mar 1;114:156-167. doi: 10.1016/j.neuropharm.2016.11.015. Epub 2016 Nov 25. Neuropharmacology. 2017. PMID: 27890602 Free PMC article.
Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice.
Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. Owens RA, et al. Among authors: mustafa ma. Neuropharmacology. 2017 Oct;125:80-86. doi: 10.1016/j.neuropharm.2017.06.032. Epub 2017 Jun 30. Neuropharmacology. 2017. PMID: 28673548 Free PMC article.
Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy.
Curry ZA, Wilkerson JL, Bagdas D, Kyte SL, Patel N, Donvito G, Mustafa MA, Poklis JL, Niphakis MJ, Hsu KL, Cravatt BF, Gewirtz DA, Damaj MI, Lichtman AH. Curry ZA, et al. Among authors: mustafa ma. J Pharmacol Exp Ther. 2018 Jul;366(1):169-183. doi: 10.1124/jpet.117.245704. Epub 2018 Mar 14. J Pharmacol Exp Ther. 2018. PMID: 29540562 Free PMC article.
N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.
Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. Donvito G, et al. Among authors: mustafa ma. Neuropharmacology. 2019 Apr;148:320-331. doi: 10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19. Neuropharmacology. 2019. PMID: 29567093 Free PMC article.
The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators.
Tseng CC, Baillie G, Donvito G, Mustafa MA, Juola SE, Zanato C, Massarenti C, Dall'Angelo S, Harrison WTA, Lichtman AH, Ross RA, Zanda M, Greig IR. Tseng CC, et al. Among authors: mustafa ma. J Med Chem. 2019 May 23;62(10):5049-5062. doi: 10.1021/acs.jmedchem.9b00252. Epub 2019 May 14. J Med Chem. 2019. PMID: 31050898 Free PMC article.
1,414 results