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DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01.
Jarman EJ, Horcas-Lopez M, Waddell SH, MacMaster S, Gournopanos K, Soong DYH, Musialik KI, Tsokkou P, Ng ME, Cambridge WA, Wilson DH, Kagey MH, Newman W, Pollard JW, Boulter L. Jarman EJ, et al. Among authors: musialik ki. Liver Int. 2023 Jan;43(1):208-220. doi: 10.1111/liv.15383. Epub 2022 Sep 15. Liver Int. 2023. PMID: 35924447 Free PMC article.
DNMT3B PWWP mutations cause hypermethylation of heterochromatin.
Taglini F, Kafetzopoulos I, Rolls W, Musialik KI, Lee HY, Zhang Y, Marenda M, Kerr L, Finan H, Rubio-Ramon C, Gautier P, Wapenaar H, Kumar D, Davidson-Smith H, Wills J, Murphy LC, Wheeler A, Wilson MD, Sproul D. Taglini F, et al. Among authors: musialik ki. EMBO Rep. 2024 Mar;25(3):1130-1155. doi: 10.1038/s44319-024-00061-5. Epub 2024 Jan 30. EMBO Rep. 2024. PMID: 38291337 Free PMC article.