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Cryo-EM structures of amyloid-β 42 filaments from human brains.
Yang Y, Arseni D, Zhang W, Huang M, Lövestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M. Yang Y, et al. Among authors: murzin ag. Science. 2022 Jan 14;375(6577):167-172. doi: 10.1126/science.abm7285. Epub 2022 Jan 13. Science. 2022. PMID: 35025654 Free PMC article.
Cryo-EM structures of tau filaments from Alzheimer's disease.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Fitzpatrick AWP, et al. Among authors: murzin ag. Nature. 2017 Jul 13;547(7662):185-190. doi: 10.1038/nature23002. Epub 2017 Jul 5. Nature. 2017. PMID: 28678775 Free PMC article.
Structures of filaments from Pick's disease reveal a novel tau protein fold.
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Falcon B, et al. Among authors: murzin ag. Nature. 2018 Sep;561(7721):137-140. doi: 10.1038/s41586-018-0454-y. Epub 2018 Aug 29. Nature. 2018. PMID: 30158706 Free PMC article.
Structures of α-synuclein filaments from multiple system atrophy.
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Schweighauser M, et al. Among authors: murzin ag. Nature. 2020 Sep;585(7825):464-469. doi: 10.1038/s41586-020-2317-6. Epub 2020 May 27. Nature. 2020. PMID: 32461689 Free PMC article.
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Shi Y, et al. Among authors: murzin ag. Acta Neuropathol. 2021 May;141(5):697-708. doi: 10.1007/s00401-021-02294-3. Epub 2021 Mar 16. Acta Neuropathol. 2021. PMID: 33723967 Free PMC article.
Structure-based classification of tauopathies.
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Shi Y, et al. Among authors: murzin ag. Nature. 2021 Oct;598(7880):359-363. doi: 10.1038/s41586-021-03911-7. Epub 2021 Sep 29. Nature. 2021. PMID: 34588692 Free PMC article.
112 results