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Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels.
Albuisson J, Murthy SE, Bandell M, Coste B, Louis-Dit-Picard H, Mathur J, Fénéant-Thibault M, Tertian G, de Jaureguiberry JP, Syfuss PY, Cahalan S, Garçon L, Toutain F, Simon Rohrlich P, Delaunay J, Picard V, Jeunemaitre X, Patapoutian A. Albuisson J, et al. Among authors: murthy se. Nat Commun. 2013;4:1884. doi: 10.1038/ncomms2899. Nat Commun. 2013. PMID: 23695678 Free PMC article.
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Ranade SS, et al. Among authors: murthy se. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52. doi: 10.1073/pnas.1409233111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958852 Free PMC article.
Structure of the mechanically activated ion channel Piezo1.
Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB. Saotome K, et al. Among authors: murthy se. Nature. 2018 Feb 22;554(7693):481-486. doi: 10.1038/nature25453. Epub 2017 Dec 20. Nature. 2018. PMID: 29261642 Free PMC article.
Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.
Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, Bandell M, Schmedt C, Wengelnik K, Su AI, Honore E, Winzeler EA, Andersen KG, Patapoutian A. Ma S, et al. Among authors: murthy se. Cell. 2018 Apr 5;173(2):443-455.e12. doi: 10.1016/j.cell.2018.02.047. Epub 2018 Mar 22. Cell. 2018. PMID: 29576450 Free PMC article.
32 results