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Using exomarkers to assess mitochondrial reactive species in vivo.
Logan A, Cochemé HM, Li Pun PB, Apostolova N, Smith RA, Larsen L, Larsen DS, James AM, Fearnley IM, Rogatti S, Prime TA, Finichiu PG, Dare A, Chouchani ET, Pell VR, Methner C, Quin C, McQuaker SJ, Krieg T, Hartley RC, Murphy MP. Logan A, et al. Among authors: murphy mp. Biochim Biophys Acta. 2014 Feb;1840(2):923-30. doi: 10.1016/j.bbagen.2013.05.026. Epub 2013 May 30. Biochim Biophys Acta. 2014. PMID: 23726990 Free article. Review.
Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.
Smith MR, Vayalil PK, Zhou F, Benavides GA, Beggs RR, Golzarian H, Nijampatnam B, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. Smith MR, et al. Among authors: murphy mp. Redox Biol. 2016 Aug;8:136-48. doi: 10.1016/j.redox.2016.01.002. Epub 2016 Jan 8. Redox Biol. 2016. PMID: 26774751 Free PMC article.
The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients.
Escribano-Lopez I, Diaz-Morales N, Rovira-Llopis S, de Marañon AM, Orden S, Alvarez A, Bañuls C, Rocha M, Murphy MP, Hernandez-Mijares A, Victor VM. Escribano-Lopez I, et al. Among authors: murphy mp. Redox Biol. 2016 Dec;10:200-205. doi: 10.1016/j.redox.2016.10.017. Epub 2016 Oct 27. Redox Biol. 2016. PMID: 27810734 Free PMC article.
MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
Shchepinova MM, Cairns AG, Prime TA, Logan A, James AM, Hall AR, Vidoni S, Arndt S, Caldwell ST, Prag HA, Pell VR, Krieg T, Mulvey JF, Yadav P, Cobley JN, Bright TP, Senn HM, Anderson RF, Murphy MP, Hartley RC. Shchepinova MM, et al. Among authors: murphy mp. Cell Chem Biol. 2017 Oct 19;24(10):1285-1298.e12. doi: 10.1016/j.chembiol.2017.08.003. Epub 2017 Sep 7. Cell Chem Biol. 2017. PMID: 28890317 Free PMC article.
794 results