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A validated regulatory network for Th17 cell specification.
Ciofani M, Madar A, Galan C, Sellars M, Mace K, Pauli F, Agarwal A, Huang W, Parkhurst CN, Muratet M, Newberry KM, Meadows S, Greenfield A, Yang Y, Jain P, Kirigin FK, Birchmeier C, Wagner EF, Murphy KM, Myers RM, Bonneau R, Littman DR. Ciofani M, et al. Among authors: murphy km. Cell. 2012 Oct 12;151(2):289-303. doi: 10.1016/j.cell.2012.09.016. Epub 2012 Sep 25. Cell. 2012. PMID: 23021777 Free PMC article.
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H. Glasmacher E, et al. Among authors: murphy tl, murphy km. Science. 2012 Nov 16;338(6109):975-80. doi: 10.1126/science.1228309. Epub 2012 Sep 13. Science. 2012. PMID: 22983707 Free PMC article.
Th17: an effector CD4 T cell lineage with regulatory T cell ties.
Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM. Weaver CT, et al. Among authors: murphy km. Immunity. 2006 Jun;24(6):677-688. doi: 10.1016/j.immuni.2006.06.002. Immunity. 2006. PMID: 16782025 Free article. Review.
BATF-JUN is critical for IRF4-mediated transcription in T cells.
Li P, Spolski R, Liao W, Wang L, Murphy TL, Murphy KM, Leonard WJ. Li P, et al. Among authors: murphy tl, murphy km. Nature. 2012 Oct 25;490(7421):543-6. doi: 10.1038/nature11530. Epub 2012 Sep 19. Nature. 2012. PMID: 22992523 Free PMC article.
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.
Nixon BG, Kuo F, Ji L, Liu M, Capistrano K, Do M, Franklin RA, Wu X, Kansler ER, Srivastava RM, Purohit TA, Sanchez A, Vuong L, Krishna C, Wang X, Morse Iii HC, Hsieh JJ, Chan TA, Murphy KM, Moon JJ, Hakimi AA, Li MO. Nixon BG, et al. Among authors: murphy km. Immunity. 2022 Nov 8;55(11):2044-2058.e5. doi: 10.1016/j.immuni.2022.10.002. Epub 2022 Oct 25. Immunity. 2022. PMID: 36288724 Free PMC article.
603 results