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The NAD(+) salvage pathway modulates cancer cell viability via p73.
Sharif T, Ahn DG, Liu RZ, Pringle E, Martell E, Dai C, Nunokawa A, Kwak M, Clements D, Murphy JP, Dean C, Marcato P, McCormick C, Godbout R, Gujar SA, Lee PW. Sharif T, et al. Among authors: murphy jp. Cell Death Differ. 2016 Apr;23(4):669-80. doi: 10.1038/cdd.2015.134. Epub 2015 Nov 20. Cell Death Differ. 2016. PMID: 26586573 Free PMC article.
Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1.
Coyle KM, Murphy JP, Vidovic D, Vaghar-Kashani A, Dean CA, Sultan M, Clements D, Wallace M, Thomas ML, Hundert A, Giacomantonio CA, Helyer L, Gujar SA, Lee PW, Weaver IC, Marcato P. Coyle KM, et al. Among authors: murphy jp. Oncotarget. 2016 Jul 12;7(28):44096-44112. doi: 10.18632/oncotarget.9858. Oncotarget. 2016. PMID: 27286452 Free PMC article.
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC. German NJ, et al. Among authors: murphy jp. Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014. Mol Cell. 2016. PMID: 27635760 Free PMC article.
323 results