Murphy JM - Search Results

1

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.

Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS. Murphy JM, et al. Immunity. 2013 Sep 19;39(3):443-53. doi: 10.1016/j.immuni.2013.06.018. Epub 2013 Sep 5. Immunity. 2013. PMID: 24012422 Free article.

2

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice.

Kauppi M, Murphy JM, de Graaf CA, Hyland CD, Greig KT, Metcalf D, Hilton AA, Nicola NA, Kile BT, Hilton DJ, Alexander WS. Kauppi M, et al. Among authors: murphy jm. Blood. 2008 Oct 15;112(8):3148-53. doi: 10.1182/blood-2007-10-119677. Epub 2008 Aug 6. Blood. 2008. PMID: 18684867 Free PMC article.

3

A convenient method for preparation of an engineered mouse interleukin-3 analog with high solubility and wild-type bioactivity.

Murphy JM, Metcalf D, Young IG, Hilton DJ. Murphy JM, et al. Growth Factors. 2010 Apr;28(2):104-10. doi: 10.3109/08977190903443048. Growth Factors. 2010. PMID: 19961363

4

Critical roles for c-Myb in lymphoid priming and early B-cell development.

Greig KT, de Graaf CA, Murphy JM, Carpinelli MR, Pang SH, Frampton J, Kile BT, Hilton DJ, Nutt SL. Greig KT, et al. Among authors: murphy jm. Blood. 2010 Apr 8;115(14):2796-805. doi: 10.1182/blood-2009-08-239210. Epub 2010 Feb 3. Blood. 2010. PMID: 20130238 Free PMC article.

5

Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity.

Babon JJ, Kershaw NJ, Murphy JM, Varghese LN, Laktyushin A, Young SN, Lucet IS, Norton RS, Nicola NA. Babon JJ, et al. Among authors: murphy jm. Immunity. 2012 Feb 24;36(2):239-50. doi: 10.1016/j.immuni.2011.12.015. Immunity. 2012. PMID: 22342841 Free PMC article.

6

Epigenetic regulator Smchd1 functions as a tumor suppressor.

Leong HS, Chen K, Hu Y, Lee S, Corbin J, Pakusch M, Murphy JM, Majewski IJ, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME. Leong HS, et al. Among authors: murphy jm. Cancer Res. 2013 Mar 1;73(5):1591-9. doi: 10.1158/0008-5472.CAN-12-3019. Epub 2012 Dec 26. Cancer Res. 2013. PMID: 23269277

7

In vitro JAK kinase activity and inhibition assays.

Babon JJ, Murphy JM. Babon JJ, et al. Among authors: murphy jm. Methods Mol Biol. 2013;967:39-55. doi: 10.1007/978-1-62703-242-1_3. Methods Mol Biol. 2013. PMID: 23296720

8

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

Moujalled DM, Cook WD, Okamoto T, Murphy J, Lawlor KE, Vince JE, Vaux DL. Moujalled DM, et al. Cell Death Dis. 2013 Jan 17;4(1):e465. doi: 10.1038/cddis.2012.201. Cell Death Dis. 2013. PMID: 23328672 Free PMC article.

9

SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.

Kershaw NJ, Murphy JM, Liau NP, Varghese LN, Laktyushin A, Whitlock EL, Lucet IS, Nicola NA, Babon JJ. Kershaw NJ, et al. Among authors: murphy jm. Nat Struct Mol Biol. 2013 Apr;20(4):469-76. doi: 10.1038/nsmb.2519. Epub 2013 Mar 3. Nat Struct Mol Biol. 2013. PMID: 23454976 Free PMC article.

10

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

Etemadi N, Holien JK, Chau D, Dewson G, Murphy JM, Alexander WS, Parker MW, Silke J, Nachbur U. Etemadi N, et al. Among authors: murphy jm. FEBS J. 2013 Nov;280(21):5283-97. doi: 10.1111/febs.12419. Epub 2013 Aug 2. FEBS J. 2013. PMID: 23815148 Free article.

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