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Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers.
Kerstan A, Dieter K, Niebergall-Roth E, Klingele S, Jünger M, Hasslacher C, Daeschlein G, Stemler L, Meyer-Pannwitt U, Schubert K, Klausmann G, Raab T, Goebeler M, Kraft K, Esterlechner J, Schröder HM, Sadeghi S, Ballikaya S, Gasser M, Waaga-Gasser AM, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Kerstan A, et al. Among authors: murphy gf. Stem Cell Res Ther. 2022 Sep 5;13(1):455. doi: 10.1186/s13287-022-03156-9. Stem Cell Res Ther. 2022. PMID: 36064604 Free PMC article. Clinical Trial.
ABCB5 Identifies Immunoregulatory Dermal Cells.
Schatton T, Yang J, Kleffel S, Uehara M, Barthel SR, Schlapbach C, Zhan Q, Dudeney S, Mueller H, Lee N, de Vries JC, Meier B, Vander Beken S, Kluth MA, Ganss C, Sharpe AH, Waaga-Gasser AM, Sayegh MH, Abdi R, Scharffetter-Kochanek K, Murphy GF, Kupper TS, Frank NY, Frank MH. Schatton T, et al. Among authors: murphy gf. Cell Rep. 2015 Sep 8;12(10):1564-74. doi: 10.1016/j.celrep.2015.08.010. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321644 Free PMC article.
In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials.
Tappenbeck N, Schröder HM, Niebergall-Roth E, Hassinger F, Dehio U, Dieter K, Kraft K, Kerstan A, Esterlechner J, Frank NY, Scharffetter-Kochanek K, Murphy GF, Orgill DP, Beck J, Frank MH, Ganss C, Kluth MA. Tappenbeck N, et al. Among authors: murphy gf. Cytotherapy. 2019 May;21(5):546-560. doi: 10.1016/j.jcyt.2018.12.005. Epub 2019 Mar 14. Cytotherapy. 2019. PMID: 30878384 Free PMC article.
Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data.
Kerstan A, Niebergall-Roth E, Esterlechner J, Schröder HM, Gasser M, Waaga-Gasser AM, Goebeler M, Rak K, Schrüfer P, Endres S, Hagenbusch P, Kraft K, Dieter K, Ballikaya S, Stemler N, Sadeghi S, Tappenbeck N, Murphy GF, Orgill DP, Frank NY, Ganss C, Scharffetter-Kochanek K, Frank MH, Kluth MA. Kerstan A, et al. Among authors: murphy gf. Cytotherapy. 2021 Feb;23(2):165-175. doi: 10.1016/j.jcyt.2020.08.012. Epub 2020 Oct 1. Cytotherapy. 2021. PMID: 33011075 Free PMC article.
Identification of cells initiating human melanomas.
Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M, Zhan Q, Jordan S, Duncan LM, Weishaupt C, Fuhlbrigge RC, Kupper TS, Sayegh MH, Frank MH. Schatton T, et al. Among authors: murphy gf. Nature. 2008 Jan 17;451(7176):345-9. doi: 10.1038/nature06489. Nature. 2008. PMID: 18202660 Free PMC article.
Modulation of T-cell activation by malignant melanoma initiating cells.
Schatton T, Schütte U, Frank NY, Zhan Q, Hoerning A, Robles SC, Zhou J, Hodi FS, Spagnoli GC, Murphy GF, Frank MH. Schatton T, et al. Among authors: murphy gf. Cancer Res. 2010 Jan 15;70(2):697-708. doi: 10.1158/0008-5472.CAN-09-1592. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068175 Free PMC article.
Isolation of tumorigenic circulating melanoma cells.
Ma J, Lin JY, Alloo A, Wilson BJ, Schatton T, Zhan Q, Murphy GF, Waaga-Gasser AM, Gasser M, Stephen Hodi F, Frank NY, Frank MH. Ma J, et al. Among authors: murphy gf. Biochem Biophys Res Commun. 2010 Nov 26;402(4):711-7. doi: 10.1016/j.bbrc.2010.10.091. Epub 2010 Oct 25. Biochem Biophys Res Commun. 2010. PMID: 20977885 Free PMC article.
VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth.
Frank NY, Schatton T, Kim S, Zhan Q, Wilson BJ, Ma J, Saab KR, Osherov V, Widlund HR, Gasser M, Waaga-Gasser AM, Kupper TS, Murphy GF, Frank MH. Frank NY, et al. Among authors: murphy gf. Cancer Res. 2011 Feb 15;71(4):1474-85. doi: 10.1158/0008-5472.CAN-10-1660. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212411 Free PMC article.
410 results