Murphy BM - Search Results

1

Targeting the apoptosis pathway to treat tumours of the paediatric nervous system.

Fitzgerald MC, O'Halloran PJ, Connolly NMC, Murphy BM. Fitzgerald MC, et al. Among authors: murphy bm. Cell Death Dis. 2022 May 14;13(5):460. doi: 10.1038/s41419-022-04900-y. Cell Death Dis. 2022. PMID: 35568716 Free PMC article. Review.

2

Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.

Murphy ÁC, Weyhenmeyer B, Schmid J, Kilbride SM, Rehm M, Huber HJ, Senft C, Weissenberger J, Seifert V, Dunst M, Mittelbronn M, Kögel D, Prehn JH, Murphy BM. Murphy ÁC, et al. Among authors: murphy bm. Cell Death Dis. 2013 May 16;4(5):e629. doi: 10.1038/cddis.2013.157. Cell Death Dis. 2013. PMID: 23681224 Free PMC article.

3

Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis.

Murphy ÁC, Weyhenmeyer B, Noonan J, Kilbride SM, Schimansky S, Loh KP, Kögel D, Letai AG, Prehn JH, Murphy BM. Murphy ÁC, et al. Among authors: murphy bm. Apoptosis. 2014 Apr;19(4):629-42. doi: 10.1007/s10495-013-0935-2. Apoptosis. 2014. PMID: 24213561 Free PMC article.

4

Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.

Weyhenmeyer BC, Noonan J, Würstle ML, Lincoln FA, Johnston G, Rehm M, Murphy BM. Weyhenmeyer BC, et al. Among authors: murphy bm. Oncotarget. 2016 Sep 20;7(38):61295-61311. doi: 10.18632/oncotarget.10973. Oncotarget. 2016. PMID: 27494880 Free PMC article.

5

Targeting Autophagy in Glioblastoma.

Noonan J, Zarrer J, Murphy BM. Noonan J, et al. Among authors: murphy bm. Crit Rev Oncog. 2016;21(3-4):241-252. doi: 10.1615/CritRevOncog.2016017008. Crit Rev Oncog. 2016. PMID: 27915974 Review.

6

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism.

Lincoln FA, Imig D, Boccellato C, Juric V, Noonan J, Kontermann RE, Allgöwer F, Murphy BM, Rehm M. Lincoln FA, et al. Among authors: murphy bm. Cell Death Dis. 2018 Nov 1;9(11):1112. doi: 10.1038/s41419-018-1160-2. Cell Death Dis. 2018. PMID: 30385739 Free PMC article.

7

Ni(II), Pd(II), and Pt(II) Complexes of the Hedgehog Pathway Inhibitor GANT61-D.

Ryan AL, Fitzgerald MC, Ozsváth A, Twamley B, Buglyó P, Murphy BM, Griffith DM. Ryan AL, et al. Among authors: murphy bm. Inorg Chem. 2019 Dec 2;58(23):16075-16086. doi: 10.1021/acs.inorgchem.9b02632. Epub 2019 Nov 15. Inorg Chem. 2019. PMID: 31729870

8

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist.

Boccellato C, Kolbe E, Peters N, Juric V, Fullstone G, Verreault M, Idbaih A, Lamfers MLM, Murphy BM, Rehm M. Boccellato C, et al. Among authors: murphy bm. Cell Death Dis. 2021 Jun 24;12(7):647. doi: 10.1038/s41419-021-03927-x. Cell Death Dis. 2021. PMID: 34168123 Free PMC article.

9

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation.

Juric V, Hudson L, Fay J, Richards CE, Jahns H, Verreault M, Bielle F, Idbaih A, Lamfers MLM, Hopkins AM, Rehm M, Murphy BM. Juric V, et al. Among authors: murphy bm. Cell Death Dis. 2021 Aug 3;12(8):763. doi: 10.1038/s41419-021-04050-7. Cell Death Dis. 2021. PMID: 34344865 Free PMC article.

10

PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours.

Davern M, Fitzgerald MC, Buckley CE, Heeran AB, Donlon NE, McGrath J, O' Connell F, Deshpande MR, Hayes C, MacDonald J, Sheppard AD, Reynolds JV, Maher SG, Lynam-Lennon N, Murphy B, Lysaght J. Davern M, et al. Transl Oncol. 2022 May;19:101381. doi: 10.1016/j.tranon.2022.101381. Epub 2022 Mar 1. Transl Oncol. 2022. PMID: 35245832 Free PMC article.

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