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Comparative analysis of deeply phenotyped GBM cohorts of 'short-term' and 'long-term' survivors.
Biswas A, Salvucci M, Connor K, Düssmann H, Carberry S, Fichtner M, King E, Murphy B, O'Farrell AC, Cryan J, Beausang A, Heffernan J, Cremona M, Hennessy BT, Clerkin J, Sweeney KJ, MacNally S, Brett F, O'Halloran P, Bacon O, Furney S, Verreault M, Quissac E, Bielle F, Ahmed MH, Idbaih A, Leenstra S, Ntafoulis I, Fabro F, Lamfers M, Golebiewska A, Hertel F, Niclou SP, Yen RTC, Kremer A, Dilcan G, Lodi F, Arijs I, Lambrechts D, Purushothama MK, Kel A, Byrne AT, Prehn JHM. Biswas A, et al. Among authors: murphy b. J Neurooncol. 2023 Jun;163(2):327-338. doi: 10.1007/s11060-023-04341-3. Epub 2023 May 26. J Neurooncol. 2023. PMID: 37237151 Free PMC article.
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.
Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Engel T, et al. FASEB J. 2010 Mar;24(3):853-61. doi: 10.1096/fj.09-145870. Epub 2009 Nov 4. FASEB J. 2010. PMID: 19890018 Free PMC article.
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters the phenotype of epilepsy in the long-term, supporting the concept that apoptotic pathway activation is a trigger of epileptogenesis.-Engel, …
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters t …
Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.
Murphy ÁC, Weyhenmeyer B, Schmid J, Kilbride SM, Rehm M, Huber HJ, Senft C, Weissenberger J, Seifert V, Dunst M, Mittelbronn M, Kögel D, Prehn JH, Murphy BM. Murphy ÁC, et al. Among authors: murphy bm. Cell Death Dis. 2013 May 16;4(5):e629. doi: 10.1038/cddis.2013.157. Cell Death Dis. 2013. PMID: 23681224 Free PMC article.
Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis.
Murphy ÁC, Weyhenmeyer B, Noonan J, Kilbride SM, Schimansky S, Loh KP, Kögel D, Letai AG, Prehn JH, Murphy BM. Murphy ÁC, et al. Among authors: murphy bm. Apoptosis. 2014 Apr;19(4):629-42. doi: 10.1007/s10495-013-0935-2. Apoptosis. 2014. PMID: 24213561 Free PMC article.
System-based approaches as prognostic tools for glioblastoma.
Salvucci M, Zakaria Z, Carberry S, Tivnan A, Seifert V, Kögel D, Murphy BM, Prehn JHM. Salvucci M, et al. BMC Cancer. 2019 Nov 12;19(1):1092. doi: 10.1186/s12885-019-6280-2. BMC Cancer. 2019. PMID: 31718568 Free PMC article. Review.
3,132 results