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Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, Roady PJ, Holler JT, Khandelwal A, SantaMaria AM, Sanchez H, Juvvadi PR, Johns G, Hageman MJ, Krise J, Gebremariam T, Youssef EG, Bartizal K, Marr KA, Steinbach WJ, Ibrahim AS, Patterson TF, Wiederhold NP, Andes DR, Pogorelov TV, Schwieters CD, Fan TM, Rienstra CM, Burke MD. Maji A, et al. Among authors: murhade g. Nature. 2023 Nov;623(7989):1079-1085. doi: 10.1038/s41586-023-06710-4. Epub 2023 Nov 8. Nature. 2023. PMID: 37938782 Free PMC article.
Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues.
Nicolaou KC, Krieger J, Murhade GM, Subramanian P, Dherange BD, Vourloumis D, Munneke S, Lin B, Gu C, Sarvaiaya H, Sandoval J, Zhang Z, Aujay M, Purcell JW, Gavrilyuk J. Nicolaou KC, et al. Among authors: murhade gm. J Am Chem Soc. 2020 Sep 9;142(36):15476-15487. doi: 10.1021/jacs.0c07094. Epub 2020 Aug 27. J Am Chem Soc. 2020. PMID: 32852944
Catalytic palladium-oxyallyl cycloaddition.
Trost BM, Huang Z, Murhade GM. Trost BM, et al. Among authors: murhade gm. Science. 2018 Nov 2;362(6414):564-568. doi: 10.1126/science.aau4821. Science. 2018. PMID: 30385573