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HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin.
Muretta JM, Rajasekaran D, Blat Y, Little S, Myers M, Nair C, Burdekin B, Yuen SL, Jimenez N, Guhathakurta P, Wilson A, Thompson AR, Surti N, Connors D, Chase P, Harden D, Barbieri CM, Adam L, Thomas DD. Muretta JM, et al. SLAS Discov. 2023 Jul;28(5):223-232. doi: 10.1016/j.slasd.2023.06.001. Epub 2023 Jun 10. SLAS Discov. 2023. PMID: 37307989 Free PMC article.
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors.
Majumdar A, Burban DJ, Muretta JM, Thompson AR, Engel TA, Rasmussen DM, Subrahmanian MV, Veglia G, Thomas DD, Levinson NM. Majumdar A, et al. Among authors: muretta jm. Nat Chem Biol. 2021 Apr;17(4):456-464. doi: 10.1038/s41589-020-00725-y. Epub 2021 Feb 1. Nat Chem Biol. 2021. PMID: 33526892 Free PMC article.
Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy.
Guhathakurta P, Carter AL, Thompson AR, Kurila D, LaFrence J, Zhang L, Trask JR, Vanderheyden B, Muretta JM, Ervasti JM, Thomas DD. Guhathakurta P, et al. Among authors: muretta jm. J Biol Chem. 2022 Dec;298(12):102675. doi: 10.1016/j.jbc.2022.102675. Epub 2022 Nov 11. J Biol Chem. 2022. PMID: 36372234 Free PMC article.
33 results