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Suspected limited efficacy of γ-secretase modulators.
Kakuda N, Akazawa K, Hatsuta H, Murayama S, Ihara Y; Japanese Alzheimer's Disease Neuroimaging Initiative. Kakuda N, et al. Among authors: murayama s. Neurobiol Aging. 2013 Apr;34(4):1101-4. doi: 10.1016/j.neurobiolaging.2012.08.017. Epub 2012 Oct 9. Neurobiol Aging. 2013. PMID: 23058852
Lewy body pathology involves cutaneous nerves.
Ikemura M, Saito Y, Sengoku R, Sakiyama Y, Hatsuta H, Kanemaru K, Sawabe M, Arai T, Ito G, Iwatsubo T, Fukayama M, Murayama S. Ikemura M, et al. Among authors: murayama s. J Neuropathol Exp Neurol. 2008 Oct;67(10):945-53. doi: 10.1097/NEN.0b013e318186de48. J Neuropathol Exp Neurol. 2008. PMID: 18800013
Neuropathological asymmetry in argyrophilic grain disease.
Adachi T, Saito Y, Hatsuta H, Funabe S, Tokumaru AM, Ishii K, Arai T, Sawabe M, Kanemaru K, Miyashita A, Kuwano R, Nakashima K, Murayama S. Adachi T, et al. Among authors: murayama s. J Neuropathol Exp Neurol. 2010 Jul;69(7):737-44. doi: 10.1097/NEN.0b013e3181e5ae5c. J Neuropathol Exp Neurol. 2010. PMID: 20535032
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease.
Murakami K, Murata N, Noda Y, Tahara S, Kaneko T, Kinoshita N, Hatsuta H, Murayama S, Barnham KJ, Irie K, Shirasawa T, Shimizu T. Murakami K, et al. Among authors: murayama s. J Biol Chem. 2011 Dec 30;286(52):44557-68. doi: 10.1074/jbc.M111.279208. Epub 2011 Nov 9. J Biol Chem. 2011. PMID: 22072713 Free PMC article.
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
Kakuda N, Shoji M, Arai H, Furukawa K, Ikeuchi T, Akazawa K, Takami M, Hatsuta H, Murayama S, Hashimoto Y, Miyajima M, Arai H, Nagashima Y, Yamaguchi H, Kuwano R, Nagaike K, Ihara Y; Japanese Alzheimer's Disease Neuroimaging Initiative. Kakuda N, et al. Among authors: murayama s. EMBO Mol Med. 2012 Apr;4(4):344-52. doi: 10.1002/emmm.201200214. Epub 2012 Feb 21. EMBO Mol Med. 2012. PMID: 22354516 Free PMC article.
1,133 results