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A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H. Fujita K, et al. Among authors: murata m. Nat Commun. 2013;4:1816. doi: 10.1038/ncomms2828. Nat Commun. 2013. PMID: 23652004 Free PMC article.
Mutant huntingtin impairs Ku70-mediated DNA repair.
Enokido Y, Tamura T, Ito H, Arumughan A, Komuro A, Shiwaku H, Sone M, Foulle R, Sawada H, Ishiguro H, Ono T, Murata M, Kanazawa I, Tomilin N, Tagawa K, Wanker EE, Okazawa H. Enokido Y, et al. Among authors: murata m. J Cell Biol. 2010 May 3;189(3):425-43. doi: 10.1083/jcb.200905138. J Cell Biol. 2010. PMID: 20439996 Free PMC article.
A novel form of necrosis, TRIAD, occurs in human Huntington's disease.
Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, Tagawa K, Akashi T, Eishi Y, Okazawa H. Yamanishi E, et al. Among authors: murata m. Acta Neuropathol Commun. 2017 Mar 8;5(1):19. doi: 10.1186/s40478-017-0420-1. Acta Neuropathol Commun. 2017. PMID: 28274274 Free PMC article.
Variants associated with Gaucher disease in multiple system atrophy.
Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Mitsui J, et al. Among authors: murata m. Ann Clin Transl Neurol. 2015 Apr;2(4):417-26. doi: 10.1002/acn3.185. Epub 2015 Feb 28. Ann Clin Transl Neurol. 2015. PMID: 25909086 Free PMC article.
Tailor-made RNAi knockdown against triplet repeat disease-causing alleles.
Takahashi M, Watanabe S, Murata M, Furuya H, Kanazawa I, Wada K, Hohjoh H. Takahashi M, et al. Among authors: murata m. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21731-6. doi: 10.1073/pnas.1012153107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098280 Free PMC article.
3,241 results