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Year Number of Results
2005 1
2006 2
2007 2
2008 1
2010 2
2011 2
2012 1
2013 1
2014 2
2015 4
2016 1
2017 2
2018 1
2019 1
2020 2
2021 1
2022 2
2024 0

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26 results

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Page 1
Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.
Yang Z, Loy J, Poirson B, Dai Y, Rajendran S, Xu S, Spires V, Gururajan M, Lin Z, Arbanas J, Carl S, Pace S, Wang Y, Mehl J, Vasudevan K, Spires T, Novosiadly R, Coker S, Perez R, Covello K, Morin P, Graziano R, Broz M, Lehman-McKeeman L. Yang Z, et al. Among authors: gururajan m. Front Pharmacol. 2022 Jun 20;13:829063. doi: 10.3389/fphar.2022.829063. eCollection 2022. Front Pharmacol. 2022. PMID: 35795558 Free PMC article.
Target-Mediated Drug Disposition Affects the Pharmacokinetics of Interleukin-10 Fragment Crystallizable Fusion Proteins at Pharmacologically Active Doses.
Yang Z, Rajendran S, Spires V, Poirson B, Gururajan M, Lin Z, Arbanas J, Krystek S, Loy J, Cheng Y, Carl S, Pace S, Wang Y, Mehl J, Xu S, Vasudevan K, Broz M, Lehman-McKeeman L, Morin P, Graziano RF. Yang Z, et al. Among authors: gururajan m. Drug Metab Dispos. 2022 Jul;50(7):898-908. doi: 10.1124/dmd.121.000799. Epub 2022 May 11. Drug Metab Dispos. 2022. PMID: 35545256
Substituted diaryl ether compounds as retinoic acid-related orphan Receptor-γt (RORγt) agonists.
Ruan Z, Park PK, Wei D, Purandare A, Wan H, O'Malley D, Stachura S, Perez H, Cavallaro CL, Weigelt CA, Sack JS, Ruzanov M, Khan J, Gururajan M, Wong JJ, Huang Y, Yarde M, Li Z, Chen C, Sun H, Borowski V, Xie JH, Anthony M, Agler M, Fink BE, Harikrishnan LS. Ruan Z, et al. Among authors: gururajan m. Bioorg Med Chem Lett. 2021 Mar 1;35:127778. doi: 10.1016/j.bmcl.2021.127778. Epub 2021 Jan 8. Bioorg Med Chem Lett. 2021. PMID: 33422603
Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists.
Harikrishnan LS, Gill P, Kamau MG, Qin LY, Ruan Z, O'Malley D, Huynh T, Stachura S, Cavallaro CL, Lu Z, J-W Duan J, Weigelt CA, Sack JS, Ruzanov M, Khan J, Gururajan M, Wong JJ, Huang Y, Yarde M, Li Z, Chen C, Sun H, Borowski V, Murtaza A, Fink BE. Harikrishnan LS, et al. Among authors: gururajan m. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127204. doi: 10.1016/j.bmcl.2020.127204. Epub 2020 Apr 20. Bioorg Med Chem Lett. 2020. PMID: 32334911
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity.
Moral JA, Leung J, Rojas LA, Ruan J, Zhao J, Sethna Z, Ramnarain A, Gasmi B, Gururajan M, Redmond D, Askan G, Bhanot U, Elyada E, Park Y, Tuveson DA, Gönen M, Leach SD, Wolchok JD, DeMatteo RP, Merghoub T, Balachandran VP. Moral JA, et al. Among authors: gururajan m. Nature. 2020 Mar;579(7797):130-135. doi: 10.1038/s41586-020-2015-4. Epub 2020 Feb 19. Nature. 2020. PMID: 32076273 Free PMC article.
miRNA Characterization from the Extracellular Vesicles.
Josson S, Gururajan M, W K Chung L. Josson S, et al. Among authors: gururajan m. Bio Protoc. 2017 Feb 20;7(4):e2139. doi: 10.21769/BioProtoc.2139. eCollection 2017 Feb 20. Bio Protoc. 2017. PMID: 34458459 Free PMC article.
In situ Hybridization (ISH) and Quantum Dots (QD) of miRNAs.
Josson S, Gururajan M, W K Chung L. Josson S, et al. Among authors: gururajan m. Bio Protoc. 2017 Feb 20;7(4):e2138. doi: 10.21769/BioProtoc.2138. eCollection 2017 Feb 20. Bio Protoc. 2017. PMID: 34458458 Free PMC article.
microRNAs and Prostate Cancer.
Josson S, Chung LW, Gururajan M. Josson S, et al. Among authors: gururajan m. Adv Exp Med Biol. 2015;889:105-18. doi: 10.1007/978-3-319-23730-5_7. Adv Exp Med Biol. 2015. PMID: 26658999 Free PMC article.
SRC family kinase FYN promotes the neuroendocrine phenotype and visceral metastasis in advanced prostate cancer.
Gururajan M, Cavassani KA, Sievert M, Duan P, Lichterman J, Huang JM, Smith B, You S, Nandana S, Chu GC, Mink S, Josson S, Liu C, Morello M, Jones LW, Kim J, Freeman MR, Bhowmick N, Zhau HE, Chung LW, Posadas EM. Gururajan M, et al. Oncotarget. 2015 Dec 29;6(42):44072-83. doi: 10.18632/oncotarget.6398. Oncotarget. 2015. PMID: 26624980 Free PMC article.
26 results