Murakami K - Search Results

1

AQP5 enriches for stem cells and cancer origins in the distal stomach.

Tan SH, Swathi Y, Tan S, Goh J, Seishima R, Murakami K, Oshima M, Tsuji T, Phuah P, Tan LT, Wong E, Fatehullah A, Sheng T, Ho SWT, Grabsch HI, Srivastava S, Teh M, Denil SLIJ, Mustafah S, Tan P, Shabbir A, So J, Yeoh KG, Barker N. Tan SH, et al. Among authors: murakami k. Nature. 2020 Feb;578(7795):437-443. doi: 10.1038/s41586-020-1973-x. Epub 2020 Feb 5. Nature. 2020. PMID: 32025032 Free article.

2

Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.

Leushacke M, Tan SH, Wong A, Swathi Y, Hajamohideen A, Tan LT, Goh J, Wong E, Denil SLIJ, Murakami K, Barker N. Leushacke M, et al. Among authors: murakami k. Nat Cell Biol. 2017 Jul;19(7):774-786. doi: 10.1038/ncb3541. Epub 2017 Jun 5. Nat Cell Biol. 2017. PMID: 28581476

3

Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis.

Oshima H, Kok SY, Nakayama M, Murakami K, Voon DC, Kimura T, Oshima M. Oshima H, et al. Among authors: murakami k. FASEB J. 2019 Feb;33(2):1873-1886. doi: 10.1096/fj.201801176R. Epub 2018 Aug 29. FASEB J. 2019. PMID: 30156908 Free PMC article.

These results indicate that Stat3 is indispensable for the survival of epithelial cells through the activation of integrin signaling and the downstream FAK pathway; however, it is not required for the Wnt signaling-activated normal or tumor epithelial cells.-Oshima, H., Kok, S.-Y …

These results indicate that Stat3 is indispensable for the survival of epithelial cells through the activation of integrin signaling and the …

4

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.

Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K. Jangphattananont N, et al. Among authors: murakami k. Int J Mol Sci. 2019 Jun 17;20(12):2955. doi: 10.3390/ijms20122955. Int J Mol Sci. 2019. PMID: 31212972 Free PMC article.

5

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.

Seishima R, Leung C, Yada S, Murad KBA, Tan LT, Hajamohideen A, Tan SH, Itoh H, Murakami K, Ishida Y, Nakamizo S, Yoshikawa Y, Wong E, Barker N. Seishima R, et al. Among authors: murakami k. Nat Commun. 2019 Nov 26;10(1):5378. doi: 10.1038/s41467-019-13363-3. Nat Commun. 2019. PMID: 31772170 Free PMC article.

6

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells.

Murakami K, Terakado Y, Saito K, Jomen Y, Takeda H, Oshima M, Barker N. Murakami K, et al. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2016806118. doi: 10.1073/pnas.2016806118. Proc Natl Acad Sci U S A. 2021. PMID: 33479180 Free PMC article.

7

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation.

Kok SY, Oshima H, Takahashi K, Nakayama M, Murakami K, Ueda HR, Miyazono K, Oshima M. Kok SY, et al. Among authors: murakami k. Nat Commun. 2021 Feb 8;12(1):863. doi: 10.1038/s41467-021-21160-0. Nat Commun. 2021. PMID: 33558489 Free PMC article.

8

FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells.

Tsuji T, Maeda Y, Kita K, Murakami K, Saya H, Takemura H, Inaki N, Oshima M, Oshima H. Tsuji T, et al. Among authors: murakami k. Oncogene. 2021 Apr;40(17):3072-3086. doi: 10.1038/s41388-021-01757-x. Epub 2021 Apr 1. Oncogene. 2021. PMID: 33795838 Free PMC article.

9

A tumour-resident Lgr5⁺ stem-cell-like pool drives the establishment and progression of advanced gastric cancers.

Fatehullah A, Terakado Y, Sagiraju S, Tan TL, Sheng T, Tan SH, Murakami K, Swathi Y, Ang N, Rajarethinam R, Ming T, Tan P, Lee B, Barker N. Fatehullah A, et al. Among authors: murakami k. Nat Cell Biol. 2021 Dec;23(12):1299-1313. doi: 10.1038/s41556-021-00793-9. Epub 2021 Dec 2. Nat Cell Biol. 2021. PMID: 34857912

10

Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.

Yamamoto D, Oshima H, Wang D, Takeda H, Kita K, Lei X, Nakayama M, Murakami K, Ohama T, Takemura H, Toyota M, Suzuki H, Inaki N, Oshima M. Yamamoto D, et al. Among authors: murakami k. J Pathol. 2022 May;257(1):39-52. doi: 10.1002/path.5868. Epub 2022 Mar 4. J Pathol. 2022. PMID: 35040131 Free PMC article.

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