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PARP1 associates with R-loops to promote their resolution and genome stability.
Laspata N, Kaur P, Mersaoui SY, Muoio D, Liu ZS, Bannister MH, Nguyen HD, Curry C, Pascal JM, Poirier GG, Wang H, Masson JY, Fouquerel E. Laspata N, et al. Among authors: muoio d. Nucleic Acids Res. 2023 Mar 21;51(5):2215-2237. doi: 10.1093/nar/gkad066. Nucleic Acids Res. 2023. PMID: 36794853 Free PMC article.
SARS-CoV-2 hijacks host cell genome instability pathways.
Victor J, Jordan T, Lamkin E, Ikeh K, March A, Frere J, Crompton A, Allen L, Fanning J, Lim WY, Muoio D, Fouquerel E, Martindale R, Dewitt J, deLance N, Taatjes D, Dragon J, Holcombe R, Greenblatt M, Kaminsky D, Hong J, Zhou P, tenOever B, Chatterjee N. Victor J, et al. Among authors: muoio d. Res Sq [Preprint]. 2022 Apr 14:rs.3.rs-1556634. doi: 10.21203/rs.3.rs-1556634/v1. Res Sq. 2022. PMID: 35441168 Free PMC article. Preprint.
APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.
Datta S, Antonio BM, Zahler NH, Theile JW, Krafte D, Zhang H, Rosenberg PB, Chaves AB, Muoio DM, Zhang G, Silas D, Li G, Soldano K, Nystrom S, Ferreira D, Miller SE, Bain JR, Muehlbauer MJ, Ilkayeva O, Becker TC, Hohmeier HE, Newgard CB, Olabisi OA. Datta S, et al. Among authors: muoio dm. J Clin Invest. 2024 Jan 16;134(5):e172262. doi: 10.1172/JCI172262. J Clin Invest. 2024. PMID: 38227370 Free PMC article.
Challenges and opportunities in targeting metabolism.
Birsoy K, Chandel NS, Fendt SM, Green DR, Li X, Muoio DM. Birsoy K, et al. Among authors: muoio dm. Cell Chem Biol. 2023 Sep 21;30(9):999-1001. doi: 10.1016/j.chembiol.2023.08.016. Cell Chem Biol. 2023. PMID: 37738954
Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
Guilherme A, Rowland LA, Wetoska N, Tsagkaraki E, Santos KB, Bedard AH, Henriques F, Kelly M, Munroe S, Pedersen DJ, Ilkayeva OR, Koves TR, Tauer L, Pan M, Han X, Kim JK, Newgard CB, Muoio DM, Czech MP. Guilherme A, et al. Among authors: muoio dm. Cell Rep. 2023 May 30;42(5):112488. doi: 10.1016/j.celrep.2023.112488. Epub 2023 May 8. Cell Rep. 2023. PMID: 37163372 Free PMC article.
140 results