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Identification of drugs that restore primary cilium expression in cancer cells.
Khan NA, Willemarck N, Talebi A, Marchand A, Binda MM, Dehairs J, Rueda-Rincon N, Daniels VW, Bagadi M, Thimiri Govinda Raj DB, Vanderhoydonc F, Munck S, Chaltin P, Swinnen JV. Khan NA, et al. Among authors: munck s. Oncotarget. 2016 Mar 1;7(9):9975-92. doi: 10.18632/oncotarget.7198. Oncotarget. 2016. PMID: 26862738 Free PMC article.
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.
Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV. Rysman E, et al. Among authors: munck s. Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876798
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM. Vriens K, et al. Among authors: munck s. Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6. Nature. 2019. PMID: 30728499 Free PMC article.
Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.
Jurisch-Yaksi N, Rose AJ, Lu H, Raemaekers T, Munck S, Baatsen P, Baert V, Vermeire W, Scales SJ, Verleyen D, Vandepoel R, Tylzanowski P, Yaksi E, de Ravel T, Yost HJ, Froyen G, Arrington CB, Annaert W. Jurisch-Yaksi N, et al. Among authors: munck s. J Cell Biol. 2013 Mar 18;200(6):709-20. doi: 10.1083/jcb.201208175. Epub 2013 Mar 11. J Cell Biol. 2013. PMID: 23479743 Free PMC article.
The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation.
Lucá R, Averna M, Zalfa F, Vecchi M, Bianchi F, La Fata G, Del Nonno F, Nardacci R, Bianchi M, Nuciforo P, Munck S, Parrella P, Moura R, Signori E, Alston R, Kuchnio A, Farace MG, Fazio VM, Piacentini M, De Strooper B, Achsel T, Neri G, Neven P, Evans DG, Carmeliet P, Mazzone M, Bagni C. Lucá R, et al. Among authors: munck s. EMBO Mol Med. 2013 Oct;5(10):1523-36. doi: 10.1002/emmm.201302847. Epub 2013 Sep 16. EMBO Mol Med. 2013. PMID: 24092663 Free PMC article.
Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane.
Paparelli L, Corthout N, Pavie B, Wakefield DL, Sannerud R, Jovanovic-Talisman T, Annaert W, Munck S. Paparelli L, et al. Among authors: munck s. PLoS Comput Biol. 2016 Sep 7;12(9):e1005095. doi: 10.1371/journal.pcbi.1005095. eCollection 2016 Sep. PLoS Comput Biol. 2016. PMID: 27603951 Free PMC article.
106 results