Multhaup G - Search Results

1

APLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding.

Schauenburg L, Liebsch F, Eravci M, Mayer MC, Weise C, Multhaup G. Schauenburg L, et al. Among authors: multhaup g. Sci Rep. 2018 Jan 30;8(1):1916. doi: 10.1038/s41598-018-19530-8. Sci Rep. 2018. PMID: 29382944 Free PMC article.

2

Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization.

Mayer MC, Kaden D, Schauenburg L, Hancock MA, Voigt P, Roeser D, Barucker C, Than ME, Schaefer M, Multhaup G. Mayer MC, et al. Among authors: multhaup g. J Biol Chem. 2014 Jul 4;289(27):19019-30. doi: 10.1074/jbc.M114.570382. Epub 2014 May 22. J Biol Chem. 2014. PMID: 24855651 Free PMC article.

., Konnig, I., Roeser, D., Guhrs, K.-H., Mayer, M. C., Kaden, D., Multhaup, G., and Than, M. E. (2012) J. Mol. Biol. 416, 438-452), but unresolved is the nature and functional importance of metal ion binding to APLP1 and APLP2. ...

., Konnig, I., Roeser, D., Guhrs, K.-H., Mayer, M. C., Kaden, D., Multhaup, G., and Than, M. E. (2012) J. Mol. Biol. 416, 438- …

3

Amyloid precursor-like protein 1 (APLP1) exhibits stronger zinc-dependent neuronal adhesion than amyloid precursor protein and APLP2.

Mayer MC, Schauenburg L, Thompson-Steckel G, Dunsing V, Kaden D, Voigt P, Schaefer M, Chiantia S, Kennedy TE, Multhaup G. Mayer MC, et al. Among authors: multhaup g. J Neurochem. 2016 Apr;137(2):266-76. doi: 10.1111/jnc.13540. Epub 2016 Mar 7. J Neurochem. 2016. PMID: 26801522 Free article.

4

Impact of amyloid precursor protein hydrophilic transmembrane residues on amyloid-beta generation.

Oestereich F, Bittner HJ, Weise C, Grohmann L, Janke LK, Hildebrand PW, Multhaup G, Munter LM. Oestereich F, et al. Among authors: multhaup g. Biochemistry. 2015 May 5;54(17):2777-84. doi: 10.1021/acs.biochem.5b00217. Epub 2015 Apr 23. Biochemistry. 2015. PMID: 25875527

5

Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function.

Barucker C, Bittner HJ, Chang PK, Cameron S, Hancock MA, Liebsch F, Hossain S, Harmeier A, Shaw H, Charron FM, Gensler M, Dembny P, Zhuang W, Schmitz D, Rabe JP, Rao Y, Lurz R, Hildebrand PW, McKinney RA, Multhaup G. Barucker C, et al. Among authors: multhaup g. Sci Rep. 2015 Oct 29;5:15410. doi: 10.1038/srep15410. Sci Rep. 2015. PMID: 26510576 Free PMC article.

6

Direct evidence of amyloid precursor-like protein 1 trans interactions in cell-cell adhesion platforms investigated via fluorescence fluctuation spectroscopy.

Dunsing V, Mayer M, Liebsch F, Multhaup G, Chiantia S. Dunsing V, et al. Among authors: multhaup g. Mol Biol Cell. 2017 Dec 1;28(25):3609-3620. doi: 10.1091/mbc.E17-07-0459. Epub 2017 Oct 11. Mol Biol Cell. 2017. PMID: 29021345 Free PMC article.

7

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.

Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P, Scheltens P, Poirier J, Saftig P, Bateman RJ, Breitner J, Hock C, Multhaup G. Liebsch F, et al. Among authors: multhaup g. Nat Commun. 2019 May 20;10(1):2240. doi: 10.1038/s41467-019-10152-w. Nat Commun. 2019. PMID: 31110178 Free PMC article.

8

Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study.

Iulita MF, Allard S, Richter L, Munter LM, Ducatenzeiler A, Weise C, Do Carmo S, Klein WL, Multhaup G, Cuello AC. Iulita MF, et al. Among authors: multhaup g. Acta Neuropathol Commun. 2014 Jun 5;2:61. doi: 10.1186/2051-5960-2-61. Acta Neuropathol Commun. 2014. PMID: 24903713 Free PMC article.

9

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease.

Kirabali T, Rigotti S, Siccoli A, Liebsch F, Shobo A, Hock C, Nitsch RM, Multhaup G, Kulic L. Kirabali T, et al. Among authors: multhaup g. Acta Neuropathol Commun. 2019 Dec 3;7(1):194. doi: 10.1186/s40478-019-0846-8. Acta Neuropathol Commun. 2019. PMID: 31796114 Free PMC article.

10

Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors.

Barucker C, Sommer A, Beckmann G, Eravci M, Harmeier A, Schipke CG, Brockschnieder D, Dyrks T, Althoff V, Fraser PE, Hazrati LN, George-Hyslop PS, Breitner JC, Peters O, Multhaup G. Barucker C, et al. Among authors: multhaup g. J Alzheimers Dis. 2015;44(2):613-24. doi: 10.3233/JAD-141902. J Alzheimers Dis. 2015. PMID: 25318543

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