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Structure-guided microbial targeting of antistaphylococcal prodrugs.
Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet PJ, Muller FL, Jez JM, Odom John AR. Miller JJ, et al. Among authors: muller fl. Elife. 2021 Jul 19;10:e66657. doi: 10.7554/eLife.66657. Elife. 2021. PMID: 34279224 Free PMC article.
Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB.
Mikati MO, Miller JJ, Osbourn DM, Barekatain Y, Ghebremichael N, Shah IT, Burnham CD, Heidel KM, Yan VC, Muller FL, Dowd CS, Edwards RL, Odom John AR. Mikati MO, et al. Among authors: muller fl. ACS Infect Dis. 2020 Nov 13;6(11):3064-3075. doi: 10.1021/acsinfecdis.0c00582. Epub 2020 Oct 29. ACS Infect Dis. 2020. PMID: 33118347 Free PMC article.
An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Lin YH, Satani N, Hammoudi N, Yan VC, Barekatain Y, Khadka S, Ackroyd JJ, Georgiou DK, Pham CD, Arthur K, Maxwell D, Peng Z, Leonard PG, Czako B, Pisaneschi F, Mandal P, Sun Y, Zielinski R, Pando SC, Wang X, Tran T, Xu Q, Wu Q, Jiang Y, Kang Z, Asara JM, Priebe W, Bornmann W, Marszalek JR, DePinho RA, Muller FL. Lin YH, et al. Among authors: muller fl. Nat Metab. 2020 Dec;2(12):1413-1426. doi: 10.1038/s42255-020-00313-3. Epub 2020 Nov 23. Nat Metab. 2020. PMID: 33230295 Free PMC article.
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma.
Khadka S, Arthur K, Barekatain Y, Behr E, Washington M, Ackroyd J, Crowley K, Suriyamongkol P, Lin YH, Pham CD, Zielinski R, Trujillo M, Galligan J, Georgiou DK, Asara J, Muller F. Khadka S, et al. Cancer Metab. 2021 Jun 25;9(1):27. doi: 10.1186/s40170-021-00259-4. Cancer Metab. 2021. PMID: 34172075 Free PMC article.
Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine.
Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, Poral AH, Tran T, Georgiou DK, Arthur K, Lin YH, Satani N, Ballato ES, Behr EI, deCarvalho AC, Verhaak RGW, de Groot J, Huse JT, Asara JM, Kalluri R, Muller FL. Barekatain Y, et al. Among authors: muller fl. Nat Commun. 2021 Jul 9;12(1):4228. doi: 10.1038/s41467-021-24240-3. Nat Commun. 2021. PMID: 34244484 Free PMC article.
Targeting Host Glycolysis as a Strategy for Antimalarial Development.
Jezewski AJ, Lin YH, Reisz JA, Culp-Hill R, Barekatain Y, Yan VC, D'Alessandro A, Muller FL, Odom John AR. Jezewski AJ, et al. Among authors: muller fl. Front Cell Infect Microbiol. 2021 Sep 16;11:730413. doi: 10.3389/fcimb.2021.730413. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34604112 Free PMC article.
Correction: Structure-guided microbial targeting of antistaphylococcal prodrugs.
Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet P, Muller FL, Jez J, Odom John AR. Miller JJ, et al. Among authors: muller fl. Elife. 2021 Nov 25;10:e75743. doi: 10.7554/eLife.75743. Elife. 2021. PMID: 34821554 Free PMC article.
Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers.
Yan VC, Pham CD, Ballato ES, Yang KL, Arthur K, Khadka S, Barekatain Y, Shrestha P, Tran T, Poral AH, Washington M, Raghavan S, Czako B, Pisaneschi F, Lin YH, Satani N, Hammoudi N, Ackroyd JJ, Georgiou DK, Millward SW, Muller FL. Yan VC, et al. Among authors: muller fl. J Med Chem. 2022 Oct 27;65(20):13813-13832. doi: 10.1021/acs.jmedchem.2c01039. Epub 2022 Oct 17. J Med Chem. 2022. PMID: 36251833 Free PMC article.
90 results