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Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells.
Halbrook CJ, Thurston G, Boyer S, Anaraki C, Jiménez JA, McCarthy A, Steele NG, Kerk SA, Hong HS, Lin L, Law FV, Felton C, Scipioni L, Sajjakulnukit P, Andren A, Beutel AK, Singh R, Nelson BS, Van Den Bergh F, Krall AS, Mullen PJ, Zhang L, Batra S, Morton JP, Stanger BZ, Christofk HR, Digman MA, Beard DA, Viale A, Zhang J, Crawford HC, Pasca di Magliano M, Jorgensen C, Lyssiotis CA. Halbrook CJ, et al. Among authors: mullen pj. Nat Cancer. 2022 Nov;3(11):1386-1403. doi: 10.1038/s43018-022-00463-1. Epub 2022 Nov 21. Nat Cancer. 2022. PMID: 36411320 Free PMC article.
A metabolic atlas of mouse aging.
Pilley SE, Awad D, Latumalea D, Esparza E, Zhang L, Shi X, Unfried M, Wang S, Mulondo R, Kashyap SB, Moaddeli D, Sajjakulnukit P, Sutton D, Wong H, Coakley AJ, Garcia G, Higuchi-Sanabria R, Liu S, Yu B, Tu WB, Kennedy BK, Lyssiotis CA, Mullen PJ. Pilley SE, et al. Among authors: mullen pj. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592445. doi: 10.1101/2024.05.04.592445. bioRxiv. 2024. PMID: 38746230 Free PMC article. Preprint.
The aging tumor metabolic microenvironment.
Pilley SE, Esparza E, Mullen PJ. Pilley SE, et al. Among authors: mullen pj. Curr Opin Biotechnol. 2023 Dec;84:102995. doi: 10.1016/j.copbio.2023.102995. Epub 2023 Sep 30. Curr Opin Biotechnol. 2023. PMID: 37783168 Review.
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth.
Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR. Krall AS, et al. Among authors: mullen pj. Cell Metab. 2021 May 4;33(5):1013-1026.e6. doi: 10.1016/j.cmet.2021.02.001. Epub 2021 Feb 19. Cell Metab. 2021. PMID: 33609439 Free PMC article.
A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer.
Longo J, Hamilton RJ, Masoomian M, Khurram N, Branchard E, Mullen PJ, Elbaz M, Hersey K, Chadwick D, Ghai S, Andrews DW, Chen EX, van der Kwast TH, Fleshner NE, Penn LZ. Longo J, et al. Among authors: mullen pj. Prostate Cancer Prostatic Dis. 2020 Dec;23(4):630-637. doi: 10.1038/s41391-020-0221-7. Epub 2020 Mar 13. Prostate Cancer Prostatic Dis. 2020. PMID: 32203069 Free PMC article.
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization.
Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, de Aguiar Vallim TQ, Lowry WE, Christofk HR. Sullivan WJ, et al. Among authors: mullen pj. Cell. 2018 Sep 20;175(1):117-132.e21. doi: 10.1016/j.cell.2018.08.017. Epub 2018 Sep 6. Cell. 2018. PMID: 30197082 Free PMC article.
34 results