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ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.
Singh C, Jin B, Shrestha N, Markhard AL, Panda A, Calvo SE, Deik A, Pan X, Zuckerman AL, Ben Saad A, Corey KE, Sjoquist J, Osganian S, AminiTabrizi R, Rhee EP, Shah H, Goldberger O, Mullen AC, Cracan V, Clish CB, Mootha VK, Goodman RP. Singh C, et al. Among authors: mullen ac. Cell Metab. 2024 Jan 2;36(1):144-158.e7. doi: 10.1016/j.cmet.2023.11.010. Epub 2023 Dec 14. Cell Metab. 2024. PMID: 38101397
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. Alsamman S, et al. Among authors: mullen ac. Sci Transl Med. 2020 Aug 19;12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. Sci Transl Med. 2020. PMID: 32817366 Free PMC article.
Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140.
Mehta S, Cronkite DA, Basavappa M, Saunders TL, Adiliaghdam F, Amatullah H, Morrison SA, Pagan JD, Anthony RM, Tonnerre P, Lauer GM, Lee JC, Digumarthi S, Pantano L, Ho Sui SJ, Ji F, Sadreyev R, Zhou C, Mullen AC, Kumar V, Li Y, Wijmenga C, Xavier RJ, Means TK, Jeffrey KL. Mehta S, et al. Among authors: mullen ac. Sci Immunol. 2017 Mar 3;2(9):eaag3160. doi: 10.1126/sciimmunol.aag3160. Epub 2017 Mar 3. Sci Immunol. 2017. PMID: 28783698 Free PMC article.
Physicians' Perspectives on Palliative Care for Patients With End-Stage Liver Disease: A National Survey Study.
Ufere NN, Donlan J, Waldman L, Patel A, Dienstag JL, Friedman LS, Corey KE, Hashemi N, Carolan P, Mullen AC, Thiim M, Bhan I, Nipp R, Greer J, Temel J, Chung RT, El-Jawahri A. Ufere NN, et al. Among authors: mullen ac. Liver Transpl. 2019 Jun;25(6):859-869. doi: 10.1002/lt.25469. Epub 2019 May 3. Liver Transpl. 2019. PMID: 30963669 Free PMC article.
39 results