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A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Mulder MP, Witting K, Berlin I, Pruneda JN, Wu KP, Chang JG, Merkx R, Bialas J, Groettrup M, Vertegaal AC, Schulman BA, Komander D, Neefjes J, El Oualid F, Ovaa H. Mulder MP, et al. Nat Chem Biol. 2016 Jul;12(7):523-30. doi: 10.1038/nchembio.2084. Epub 2016 May 16. Nat Chem Biol. 2016. PMID: 27182664 Free PMC article.
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, Oualid FE, Kawasaki M, Freund SMV, Ovaa H, Komander D. Mevissen TET, et al. Among authors: mulder mpc. Nature. 2016 Oct 20;538(7625):402-405. doi: 10.1038/nature19836. Epub 2016 Oct 12. Nature. 2016. PMID: 27732584 Free PMC article.
Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies.
Juenemann K, Jansen AHP, van Riel L, Merkx R, Mulder MPC, An H, Statsyuk A, Kirstein J, Ovaa H, Reits EA. Juenemann K, et al. Among authors: mulder mpc. Sci Rep. 2018 Jan 23;8(1):1405. doi: 10.1038/s41598-018-19538-0. Sci Rep. 2018. PMID: 29362455 Free PMC article.
Generation of the UFM1 Toolkit for Profiling UFM1-Specific Proteases and Ligases.
Witting KF, van der Heden van Noort GJ, Kofoed C, Talavera Ormeño C, El Atmioui D, Mulder MPC, Ovaa H. Witting KF, et al. Among authors: mulder mpc. Angew Chem Int Ed Engl. 2018 Oct 22;57(43):14164-14168. doi: 10.1002/anie.201809232. Epub 2018 Oct 1. Angew Chem Int Ed Engl. 2018. PMID: 30188611 Free PMC article.
31 results