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Human milk inhibits some enveloped virus infections, including SARS-CoV-2, in an intestinal model.
Aknouch I, Sridhar A, Freeze E, Giugliano FP, van Keulen BJ, Romijn M, Calitz C, García-Rodríguez I, Mulder L, Wildenberg ME, Muncan V, van Gils MJ, van Goudoever JB, Stittelaar KJ, Wolthers KC, Pajkrt D. Aknouch I, et al. Among authors: mulder l. Life Sci Alliance. 2022 Aug 4;5(12):e202201432. doi: 10.26508/lsa.202201432. Life Sci Alliance. 2022. PMID: 35926873 Free PMC article.
Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism.
Sridhar A, Depla JA, Mulder LA, Karelehto E, Brouwer L, Kruiswijk L, Vieira de Sá R, Meijer A, Evers MM, van Kuppeveld FJM, Pajkrt D, Wolthers KC. Sridhar A, et al. Among authors: mulder la. Microbiol Spectr. 2022 Oct 26;10(5):e0169422. doi: 10.1128/spectrum.01694-22. Epub 2022 Sep 26. Microbiol Spectr. 2022. PMID: 36154279 Free PMC article.
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
García-Rodríguez I, Moreni G, Capendale PE, Mulder L, Aknouch I, Vieira de Sá R, Johannesson N, Freeze E, van Eijk H, Koen G, Wolthers KC, Pajkrt D, Sridhar A, Calitz C. García-Rodríguez I, et al. Among authors: mulder l. Antiviral Res. 2024 Feb;222:105798. doi: 10.1016/j.antiviral.2024.105798. Epub 2024 Jan 6. Antiviral Res. 2024. PMID: 38190972 Free article.
Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease.
Capendale PE, García-Rodríguez I, Ambikan AT, Mulder LA, Depla JA, Freeze E, Koen G, Calitz C, Sood V, Vieira de Sá R, Neogi U, Pajkrt D, Sridhar A, Wolthers KC. Capendale PE, et al. Among authors: mulder la. Nat Commun. 2024 Mar 21;15(1):2532. doi: 10.1038/s41467-024-46634-9. Nat Commun. 2024. PMID: 38514653 Free PMC article.
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.
Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N; IMPACC Network; Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Phan HV, et al. Sci Transl Med. 2024 Apr 17;16(743):eadj5154. doi: 10.1126/scitranslmed.adj5154. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630846
315 results