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Haematopoietic stem cells in perisinusoidal niches are protected from ageing.
Saçma M, Pospiech J, Bogeska R, de Back W, Mallm JP, Sakk V, Soller K, Marka G, Vollmer A, Karns R, Cabezas-Wallscheid N, Trumpp A, Méndez-Ferrer S, Milsom MD, Mulaw MA, Geiger H, Florian MC. Saçma M, et al. Among authors: mulaw ma. Nat Cell Biol. 2019 Nov;21(11):1309-1320. doi: 10.1038/s41556-019-0418-y. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685996
Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift.
Hageb A, Thalheim T, Nattamai KJ, Möhrle B, Saçma M, Sakk V, Thielecke L, Cornils K, Grandy C, Port F, Gottschalk KE, Mallm JP, Glauche I, Galle J, Mulaw MA, Geiger H. Hageb A, et al. Among authors: mulaw ma. Life Sci Alliance. 2022 Apr 29;5(8):e202201408. doi: 10.26508/lsa.202201408. Print 2022 Aug. Life Sci Alliance. 2022. PMID: 35487692 Free PMC article.
Aging alters the epigenetic asymmetry of HSC division.
Florian MC, Klose M, Sacma M, Jablanovic J, Knudson L, Nattamai KJ, Marka G, Vollmer A, Soller K, Sakk V, Cabezas-Wallscheid N, Zheng Y, Mulaw MA, Glauche I, Geiger H. Florian MC, et al. Among authors: mulaw ma. PLoS Biol. 2018 Sep 20;16(9):e2003389. doi: 10.1371/journal.pbio.2003389. eCollection 2018 Sep. PLoS Biol. 2018. PMID: 30235201 Free PMC article.
Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells.
Grigoryan A, Pospiech J, Krämer S, Lipka D, Liehr T, Geiger H, Kimura H, Mulaw MA, Florian MC. Grigoryan A, et al. Among authors: mulaw ma. Stem Cell Reports. 2021 Apr 13;16(4):708-716. doi: 10.1016/j.stemcr.2021.03.007. Epub 2021 Apr 1. Stem Cell Reports. 2021. PMID: 33798450 Free PMC article.
Repolarization of HSC attenuates HSCs failure in Shwachman-Diamond syndrome.
Kumar S, Nattamai KJ, Hassan A, Amoah A, Karns R, Zhang C, Liang Y, Shimamura A, Florian MC, Bissels U, Luevano M, Bosio A, Davies SM, Mulaw M, Geiger H, Myers KC. Kumar S, et al. Leukemia. 2021 Jun;35(6):1751-1762. doi: 10.1038/s41375-020-01054-8. Epub 2020 Oct 19. Leukemia. 2021. PMID: 33077869
58 results