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Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW. Lu C, et al. Among authors: muir tw. Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272. Science. 2016. PMID: 27174990 Free PMC article.
H3R42me2a is a histone modification with positive transcriptional effects.
Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. Casadio F, et al. Among authors: muir tw. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14894-9. doi: 10.1073/pnas.1312925110. Epub 2013 Aug 26. Proc Natl Acad Sci U S A. 2013. PMID: 23980157 Free PMC article.
PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.
Diehl KL, Ge EJ, Weinberg DN, Jani KS, Allis CD, Muir TW. Diehl KL, et al. Among authors: muir tw. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22152-22157. doi: 10.1073/pnas.1911775116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611394 Free PMC article.
Spreading chromatin into chemical biology.
Allis CD, Muir TW. Allis CD, et al. Among authors: muir tw. Chembiochem. 2011 Jan 24;12(2):264-79. doi: 10.1002/cbic.201000761. Epub 2011 Jan 11. Chembiochem. 2011. PMID: 21243714 Review.
253 results