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A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
Butorac C, Muik M, Derler I, Stadlbauer M, Lunz V, Krizova A, Lindinger S, Schober R, Frischauf I, Bhardwaj R, Hediger MA, Groschner K, Romanin C. Butorac C, et al. Among authors: muik m. Cell Calcium. 2019 May;79:57-67. doi: 10.1016/j.ceca.2019.02.009. Epub 2019 Feb 23. Cell Calcium. 2019. PMID: 30831274 Free article.
Communication between N terminus and loop2 tunes Orai activation.
Fahrner M, Pandey SK, Muik M, Traxler L, Butorac C, Stadlbauer M, Zayats V, Krizova A, Plenk P, Frischauf I, Schindl R, Gruber HJ, Hinterdorfer P, Ettrich R, Romanin C, Derler I. Fahrner M, et al. Among authors: muik m. J Biol Chem. 2018 Jan 26;293(4):1271-1285. doi: 10.1074/jbc.M117.812693. Epub 2017 Dec 13. J Biol Chem. 2018. PMID: 29237733 Free PMC article.
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf I, Litviňuková M, Schober R, Zayats V, Svobodová B, Bonhenry D, Lunz V, Cappello S, Tociu L, Reha D, Stallinger A, Hochreiter A, Pammer T, Butorac C, Muik M, Groschner K, Bogeski I, Ettrich RH, Romanin C, Schindl R. Frischauf I, et al. Among authors: muik m. Sci Signal. 2017 Nov 28;10(507):eaao0358. doi: 10.1126/scisignal.aao0358. Sci Signal. 2017. PMID: 29184031 Free PMC article.
Cholesterol modulates Orai1 channel function.
Derler I, Jardin I, Stathopulos PB, Muik M, Fahrner M, Zayats V, Pandey SK, Poteser M, Lackner B, Absolonova M, Schindl R, Groschner K, Ettrich R, Ikura M, Romanin C. Derler I, et al. Among authors: muik m. Sci Signal. 2016 Jan 26;9(412):ra10. doi: 10.1126/scisignal.aad7808. Sci Signal. 2016. PMID: 26814231 Free PMC article.
36 results