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Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer-associated fibroblasts.
Cirillo F, Pellegrino M, Talia M, Perrotta ID, Rigiracciolo DC, Spinelli A, Scordamaglia D, Muglia L, Guzzi R, Miglietta AM, De Francesco EM, Belfiore A, Maggiolini M, Lappano R. Cirillo F, et al. Among authors: muglia l. Clin Transl Med. 2021 Nov;11(11):e516. doi: 10.1002/ctm2.516. Clin Transl Med. 2021. PMID: 34841688 Free PMC article.
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells.
Scordamaglia D, Cirillo F, Talia M, Santolla MF, Rigiracciolo DC, Muglia L, Zicarelli A, De Rosis S, Giordano F, Miglietta AM, De Francesco EM, Vella V, Belfiore A, Lappano R, Maggiolini M. Scordamaglia D, et al. Among authors: muglia l. J Transl Med. 2022 Jun 7;20(1):263. doi: 10.1186/s12967-022-03463-y. J Transl Med. 2022. PMID: 35672854 Free PMC article.
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells.
Talia M, Cirillo F, Spinelli A, Zicarelli A, Scordamaglia D, Muglia L, De Rosis S, Rigiracciolo DC, Filippelli G, Perrotta ID, Davoli M, De Rosa R, Macirella R, Brunelli E, Miglietta AM, Nardo B, Tosoni D, Pece S, De Francesco EM, Belfiore A, Maggiolini M, Lappano R. Talia M, et al. Among authors: muglia l. J Exp Clin Cancer Res. 2023 Jul 12;42(1):164. doi: 10.1186/s13046-023-02747-5. J Exp Clin Cancer Res. 2023. PMID: 37434266 Free PMC article.
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
Cirillo F, Talia M, Santolla MF, Pellegrino M, Scordamaglia D, Spinelli A, De Rosis S, Giordano F, Muglia L, Zicarelli A, Di Dio M, Rigiracciolo DC, Miglietta AM, Filippelli G, De Francesco EM, Belfiore A, Lappano R, Maggiolini M. Cirillo F, et al. Among authors: muglia l. Cell Death Discov. 2023 Sep 26;9(1):353. doi: 10.1038/s41420-023-01654-0. Cell Death Discov. 2023. PMID: 37749101 Free PMC article.
A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis.
Pavličev M, McDonough-Goldstein CE, Zupan AM, Muglia L, Hu YC, Kong F, Monangi N, Dagdas G, Zupančič N, Maziarz J, Sinner D, Zhang G, Wagner G, Muglia L. Pavličev M, et al. Among authors: muglia l. Nat Commun. 2024 Feb 12;15(1):1152. doi: 10.1038/s41467-024-45338-4. Nat Commun. 2024. PMID: 38346980 Free PMC article.
298 results