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Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors.
Lacey BM, Xu Z, Chai X, Laskey J, Fradera X, Mittal P, Mishra S, Piesvaux J, Saradjian P, Shaffer L, Vassileva G, Gerdt C, Wang Y, Ferguson H, Smith DM, Ballard J, Wells S, Jain R, Mueller U, Addona G, Kariv I, Methot JL, Bittinger M, Ranganath S, Mcleod R, Pasternak A, Miller JR, Xu H. Lacey BM, et al. Among authors: mueller u. SLAS Discov. 2021 Jan;26(1):88-99. doi: 10.1177/2472555220952071. Epub 2020 Aug 26. SLAS Discov. 2021. PMID: 32844715 Free article.
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor.
Nagashima K, Shumway SD, Sathyanarayanan S, Chen AH, Dolinski B, Xu Y, Keilhack H, Nguyen T, Wiznerowicz M, Li L, Lutterbach BA, Chi A, Paweletz C, Allison T, Yan Y, Munshi SK, Klippel A, Kraus M, Bobkova EV, Deshmukh S, Xu Z, Mueller U, Szewczak AA, Pan BS, Richon V, Pollock R, Blume-Jensen P, Northrup A, Andersen JN. Nagashima K, et al. Among authors: mueller u. J Biol Chem. 2011 Feb 25;286(8):6433-48. doi: 10.1074/jbc.M110.156463. Epub 2010 Nov 30. J Biol Chem. 2011. PMID: 21118801 Free PMC article.
Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
Sun L, Chen Y, Rajendran C, Mueller U, Panjikar S, Wang M, Mindnich R, Rosenthal C, Penning TM, Stöckigt J. Sun L, et al. Among authors: mueller u. J Biol Chem. 2012 Mar 30;287(14):11213-21. doi: 10.1074/jbc.M111.335521. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334702 Free PMC article.
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants.
Rosenthal C, Mueller U, Panjikar S, Sun L, Ruppert M, Zhao Y, Stöckigt J. Rosenthal C, et al. Among authors: mueller u. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1286-9. doi: 10.1107/S174430910605041X. Epub 2006 Nov 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17142919 Free PMC article.
De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse.
Lakomek K, Dickmanns A, Mueller U, Kollmann K, Deuschl F, Berndt A, Lübke T, Ficner R. Lakomek K, et al. Among authors: mueller u. Acta Crystallogr D Biol Crystallogr. 2009 Mar;65(Pt 3):220-8. doi: 10.1107/S0907444908041814. Epub 2009 Feb 20. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19237744
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570 Free article.
444 results