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Decreased levels of repulsive guidance molecule A in association with beneficial effects of repeated intrathecal triamcinolone acetonide application in progressive multiple sclerosis patients.
Müller T, Barghorn S, Lütge S, Haas T, Mueller R, Gerlach B, Öhm G, Eilert K, Trommer I, Mueller BK. Müller T, et al. Among authors: mueller r, mueller bk. J Neural Transm (Vienna). 2015 Jun;122(6):841-8. doi: 10.1007/s00702-014-1308-x. Epub 2014 Sep 11. J Neural Transm (Vienna). 2015. PMID: 25209051
Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis.
Demicheva E, Cui YF, Bardwell P, Barghorn S, Kron M, Meyer AH, Schmidt M, Gerlach B, Leddy M, Barlow E, O'Connor E, Choi CH, Huang L, Veldman GM, Rus H, Shabanzadeh AP, Tassew NG, Monnier PP, Müller T, Calabresi PA, Schoemaker H, Mueller BK. Demicheva E, et al. Among authors: mueller bk. Cell Rep. 2015 Mar 24;10(11):1887-98. doi: 10.1016/j.celrep.2015.02.048. Cell Rep. 2015. PMID: 25801027 Free article.
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
Hobson AD, Judge RA, Aguirre AL, Brown BS, Cui Y, Ding P, Dominguez E, DiGiammarino E, Egan DA, Freiberg GM, Gopalakrishnan SM, Harris CM, Honore MP, Kage KL, Kapecki NJ, Ling C, Ma J, Mack H, Mamo M, Maurus S, McRae B, Moore NS, Mueller BK, Mueller R, Namovic MT, Patel K, Pratt SD, Putman CB, Queeney KL, Sarris KK, Schaffter LM, Stoll V, Vasudevan A, Wang L, Wang L, Wirthl W, Yach K. Hobson AD, et al. Among authors: mueller r, mueller bk. J Med Chem. 2018 Dec 27;61(24):11074-11100. doi: 10.1021/acs.jmedchem.8b01098. Epub 2018 Dec 12. J Med Chem. 2018. PMID: 30384606
Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models.
Huang L, Fung E, Bose S, Popp A, Böser P, Memmott J, Kutskova YA, Miller R, Tarcsa E, Klein C, Veldman GM, Mueller BK, Cui YF. Huang L, et al. Among authors: mueller bk. Neurobiol Dis. 2021 Nov;159:105492. doi: 10.1016/j.nbd.2021.105492. Epub 2021 Aug 31. Neurobiol Dis. 2021. PMID: 34478849 Free article.
54 results