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Myeloid-specific fatty acid transport protein 4 deficiency induces a sex-dimorphic susceptibility for nonalcoholic steatohepatitis in mice fed a high-fat, high-cholesterol diet.
Göcebe D, Jansakun C, Zhang Y, Staffer S, Tuma-Kellner S, Altamura S, Muckenthaler MU, Merle U, Herrmann T, Chamulitrat W. Göcebe D, et al. Among authors: muckenthaler mu. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G389-G403. doi: 10.1152/ajpgi.00181.2022. Epub 2023 Mar 7. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36881564 Free PMC article.
Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH.
Jansakun C, Chunglok W, Altamura S, Muckenthaler M, Staffer S, Tuma-Kellner S, Merle U, Chamulitrat W. Jansakun C, et al. Biochim Biophys Acta Mol Basis Dis. 2023 Jan 1;1869(1):166590. doi: 10.1016/j.bbadis.2022.166590. Epub 2022 Nov 2. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36334837 Free article.
Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.
Klement L, Jansakun C, Yan B, Staffer S, Tuma-Kellner S, Altamura S, Muckenthaler M, Merle U, Chamulitrat W. Klement L, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):167016. doi: 10.1016/j.bbadis.2024.167016. Epub 2024 Jan 9. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38198970 Free article.
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport.
Pfeffer T, Krug SM, Kracke T, Schürfeld R, Colbatzky F, Kirschner P, Medert R, Freichel M, Schumacher D, Bartosova M, Zarogiannis SG, Muckenthaler MU, Altamura S, Pezer S, Volk N, Schwab C, Duensing S, Fleming T, Heidenreich E, Zschocke J, Hell R, Poschet G, Schmitt CP, Peters V. Pfeffer T, et al. Among authors: muckenthaler mu. Acta Physiol (Oxf). 2024 Apr;240(4):e14126. doi: 10.1111/apha.14126. Epub 2024 Mar 22. Acta Physiol (Oxf). 2024. PMID: 38517248
Dynamic YAP expression in the non-parenchymal liver cell compartment controls heterologous cell communication.
Liu K, Wehling L, Wan S, Weiler SME, Tóth M, Ibberson D, Marhenke S, Ali A, Lam M, Guo T, Pinna F, Pedrini F, Damle-Vartak A, Dropmann A, Rose F, Colucci S, Cheng W, Bissinger M, Schmitt J, Birner P, Poth T, Angel P, Dooley S, Muckenthaler MU, Longerich T, Vogel A, Heikenwälder M, Schirmacher P, Breuhahn K. Liu K, et al. Among authors: muckenthaler mu. Cell Mol Life Sci. 2024 Mar 4;81(1):115. doi: 10.1007/s00018-024-05126-1. Cell Mol Life Sci. 2024. PMID: 38436764 Free PMC article.
Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients?
Theobald V, Grünig E, Benjamin N, Seyfarth HJ, Halank M, Schneider MA, Richtmann S, Kazdal D, Hinderhofer K, Xanthouli P, Egenlauf B, Harutyunova S, Hoeper MM, Jonigk D, Sparla R, Muckenthaler MU, Eichstaedt CA. Theobald V, et al. Among authors: muckenthaler mu. Pulm Circ. 2023 Jun 7;13(2):e12242. doi: 10.1002/pul2.12242. eCollection 2023 Apr. Pulm Circ. 2023. PMID: 37292089 Free PMC article.
Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.
Samarin J, Fabrowski P, Kurilov R, Nuskova H, Hummel-Eisenbeiss J, Pink H, Li N, Weru V, Alborzinia H, Yildiz U, Grob L, Taubert M, Czech M, Morgen M, Brandstädter C, Becker K, Mao L, Jayavelu AK, Goncalves A, Uhrig U, Seiler J, Lyu Y, Diederichs S, Klingmüller U, Muckenthaler M, Kopp-Schneider A, Teleman A, Miller AK, Gunkel N. Samarin J, et al. Redox Biol. 2023 Jun;62:102639. doi: 10.1016/j.redox.2023.102639. Epub 2023 Feb 23. Redox Biol. 2023. PMID: 36958250 Free PMC article.
200 results