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Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.
Atigadda VR, Kashyap MP, Yang Z, Chattopadhyay D, Melo N, Sinha R, Belyaeva OV, Chou CF, Chang PL, Kedishvili NY, Grubbs CJ, Renfrow MB, Muccio DD, Elmets CA, Athar M. Atigadda VR, et al. Among authors: muccio dd. J Med Chem. 2022 Nov 10;65(21):14409-14423. doi: 10.1021/acs.jmedchem.2c00735. Epub 2022 Nov 1. J Med Chem. 2022. PMID: 36318154 Free PMC article.
Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics.
Melo N, Belyaeva OV, Berger WK, Halasz L, Yu J, Pilli N, Yang Z, Klyuyeva AV, Elmets CA, Atigadda V, Muccio DD, Kane MA, Nagy L, Kedishvili NY, Renfrow MB. Melo N, et al. Among authors: muccio dd. J Biol Chem. 2023 Jan;299(1):102746. doi: 10.1016/j.jbc.2022.102746. Epub 2022 Nov 24. J Biol Chem. 2023. PMID: 36436565 Free PMC article.
A Randomized, Placebo-Controlled, Double-Blind, Dose Escalation, Single Dose, and Steady-State Pharmacokinetic Study of 9cUAB30 in Healthy Volunteers.
Kolesar JM, Andrews S, Green H, Havighurst TC, Wollmer BW, DeShong K, Laux DE, Krontiras H, Muccio DD, Kim K, Grubbs CJ, House MG, Parnes HL, Heckman-Stoddard BM, Bailey HH. Kolesar JM, et al. Among authors: muccio dd. Cancer Prev Res (Phila). 2019 Dec;12(12):903-912. doi: 10.1158/1940-6207.CAPR-19-0310. Epub 2019 Sep 4. Cancer Prev Res (Phila). 2019. PMID: 31484659 Free PMC article. Clinical Trial.
Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies.
Waters AM, Stewart JE, Atigadda VR, Mroczek-Musulman E, Muccio DD, Grubbs CJ, Beierle EA. Waters AM, et al. Among authors: muccio dd. Mol Cancer Ther. 2016 May;15(5):911-21. doi: 10.1158/1535-7163.MCT-15-0521. Epub 2016 Feb 12. Mol Cancer Ther. 2016. PMID: 26873726 Free PMC article.
52 results