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Abrogation of the RNase activity of Erns in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs.
Wang M, Bohórquez JA, Hinojosa Y, Muñoz-González S, Gerber M, Coronado L, Perera CL, Liniger M, Ruggli N, Ganges L. Wang M, et al. Among authors: munoz gonzalez s. Virulence. 2021 Dec;12(1):2037-2049. doi: 10.1080/21505594.2021.1959715. Virulence. 2021. PMID: 34339338 Free PMC article.
Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus.
Coronado L, Liniger M, Muñoz-González S, Postel A, Pérez LJ, Pérez-Simó M, Perera CL, Frías-Lepoureau MT, Rosell R, Grundhoff A, Indenbirken D, Alawi M, Fischer N, Becher P, Ruggli N, Ganges L. Coronado L, et al. Vet Microbiol. 2017 Mar;201:103-112. doi: 10.1016/j.vetmic.2017.01.013. Epub 2017 Jan 17. Vet Microbiol. 2017. PMID: 28284595
Removal of the Erns RNase Activity and of the 3' Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease.
Wang M, Bohórquez JA, Muñoz-González S, Gerber M, Alberch M, Pérez-Simó M, Abad X, Liniger M, Ruggli N, Ganges L. Wang M, et al. Among authors: munoz gonzalez s. J Virol. 2022 Jul 27;96(14):e0043822. doi: 10.1128/jvi.00438-22. Epub 2022 Jun 27. J Virol. 2022. PMID: 35758667 Free PMC article.
21 results