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A versatile drug delivery system targeting senescent cells.
Muñoz-Espín D, Rovira M, Galiana I, Giménez C, Lozano-Torres B, Paez-Ribes M, Llanos S, Chaib S, Muñoz-Martín M, Ucero AC, Garaulet G, Mulero F, Dann SG, VanArsdale T, Shields DJ, Bernardos A, Murguía JR, Martínez-Máñez R, Serrano M. Muñoz-Espín D, et al. EMBO Mol Med. 2018 Sep;10(9):e9355. doi: 10.15252/emmm.201809355. EMBO Mol Med. 2018. PMID: 30012580 Free PMC article.
Programmed cell senescence during mammalian embryonic development.
Muñoz-Espín D, Cañamero M, Maraver A, Gómez-López G, Contreras J, Murillo-Cuesta S, Rodríguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M. Muñoz-Espín D, et al. Cell. 2013 Nov 21;155(5):1104-18. doi: 10.1016/j.cell.2013.10.019. Epub 2013 Nov 14. Cell. 2013. PMID: 24238962 Free article.
Cellular senescence: from physiology to pathology.
Muñoz-Espín D, Serrano M. Muñoz-Espín D, et al. Nat Rev Mol Cell Biol. 2014 Jul;15(7):482-96. doi: 10.1038/nrm3823. Nat Rev Mol Cell Biol. 2014. PMID: 24954210 Review.
Robust, universal biomarker assay to detect senescent cells in biological specimens.
Evangelou K, Lougiakis N, Rizou SV, Kotsinas A, Kletsas D, Muñoz-Espín D, Kastrinakis NG, Pouli N, Marakos P, Townsend P, Serrano M, Bartek J, Gorgoulis VG. Evangelou K, et al. Aging Cell. 2017 Feb;16(1):192-197. doi: 10.1111/acel.12545. Epub 2016 Nov 17. Aging Cell. 2017. PMID: 28165661 Free PMC article.
An OFF-ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo.
Lozano-Torres B, Galiana I, Rovira M, Garrido E, Chaib S, Bernardos A, Muñoz-Espín D, Serrano M, Martínez-Máñez R, Sancenón F. Lozano-Torres B, et al. J Am Chem Soc. 2017 Jul 5;139(26):8808-8811. doi: 10.1021/jacs.7b04985. Epub 2017 Jun 23. J Am Chem Soc. 2017. PMID: 28625064 Free article.
Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3.
Borghesan M, Fafián-Labora J, Eleftheriadou O, Carpintero-Fernández P, Paez-Ribes M, Vizcay-Barrena G, Swisa A, Kolodkin-Gal D, Ximénez-Embún P, Lowe R, Martín-Martín B, Peinado H, Muñoz J, Fleck RA, Dor Y, Ben-Porath I, Vossenkamper A, Muñoz-Espin D, O'Loghlen A. Borghesan M, et al. Cell Rep. 2019 Jun 25;27(13):3956-3971.e6. doi: 10.1016/j.celrep.2019.05.095. Cell Rep. 2019. PMID: 31242426 Free PMC article.
Targeting senescent cells in translational medicine.
Paez-Ribes M, González-Gualda E, Doherty GJ, Muñoz-Espín D. Paez-Ribes M, et al. EMBO Mol Med. 2019 Dec;11(12):e10234. doi: 10.15252/emmm.201810234. Epub 2019 Nov 19. EMBO Mol Med. 2019. PMID: 31746100 Free PMC article. Review.
Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.
González-Gualda E, Pàez-Ribes M, Lozano-Torres B, Macias D, Wilson JR 3rd, González-López C, Ou HL, Mirón-Barroso S, Zhang Z, Lérida-Viso A, Blandez JF, Bernardos A, Sancenón F, Rovira M, Fruk L, Martins CP, Serrano M, Doherty GJ, Martínez-Máñez R, Muñoz-Espín D. González-Gualda E, et al. Aging Cell. 2020 Apr;19(4):e13142. doi: 10.1111/acel.13142. Epub 2020 Mar 31. Aging Cell. 2020. PMID: 32233024 Free PMC article.
Cellular senescence in cancer: from mechanisms to detection.
Ou HL, Hoffmann R, González-López C, Doherty GJ, Korkola JE, Muñoz-Espín D. Ou HL, et al. Among authors: munoz espin d. Mol Oncol. 2021 Oct;15(10):2634-2671. doi: 10.1002/1878-0261.12807. Epub 2020 Oct 22. Mol Oncol. 2021. PMID: 32981205 Free PMC article. Review.
38 results