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IL-23 blockade with guselkumab potentially modifies psoriasis pathogenesis: rationale and study protocol of a phase 3b, randomised, double-blind, multicentre study in participants with moderate-to-severe plaque-type psoriasis (GUIDE).
Eyerich K, Weisenseel P, Pinter A, Schäkel K, Asadullah K, Wegner S, Muñoz-Elias EJ, Bartz H, Taut FJH, Reich K. Eyerich K, et al. Among authors: munoz elias ej. BMJ Open. 2021 Sep 13;11(9):e049822. doi: 10.1136/bmjopen-2021-049822. BMJ Open. 2021. PMID: 34518264 Free PMC article.
Extension of ustekinumab maintenance dosing interval in moderate-to-severe psoriasis: results of a phase IIIb, randomized, double-blinded, active-controlled, multicentre study (PSTELLAR).
Blauvelt A, Ferris LK, Yamauchi PS, Qureshi A, Leonardi CL, Farahi K, Fakharzadeh S, Hsu MC, Li S, Chevrier M, Smith K, Goyal K, Chen Y, Muñoz-Elías EJ, Callis Duffin K. Blauvelt A, et al. Br J Dermatol. 2017 Dec;177(6):1552-1561. doi: 10.1111/bjd.15722. Epub 2017 Nov 16. Br J Dermatol. 2017. PMID: 28600818 Clinical Trial.
Guselkumab Efficacy after Withdrawal Is Associated with Suppression of Serum IL-23-Regulated IL-17 and IL-22 in Psoriasis: VOYAGE 2 Study.
Gordon KB, Armstrong AW, Foley P, Song M, Shen YK, Li S, Muñoz-Elías EJ, Branigan P, Liu X, Reich K. Gordon KB, et al. Among authors: munoz elias ej. J Invest Dermatol. 2019 Dec;139(12):2437-2446.e1. doi: 10.1016/j.jid.2019.05.016. Epub 2019 Jun 15. J Invest Dermatol. 2019. PMID: 31207232 Free article. Clinical Trial.
Longitudinal Study of the Psoriasis-Associated Skin Microbiome during Therapy with Ustekinumab in a Randomized Phase 3b Clinical Trial.
Loesche MA, Farahi K, Capone K, Fakharzadeh S, Blauvelt A, Duffin KC, DePrimo SE, Muñoz-Elías EJ, Brodmerkel C, Dasgupta B, Chevrier M, Smith K, Horwinski J, Tyldsley A, Grice EA. Loesche MA, et al. Among authors: munoz elias ej. J Invest Dermatol. 2018 Sep;138(9):1973-1981. doi: 10.1016/j.jid.2018.03.1501. Epub 2018 Mar 17. J Invest Dermatol. 2018. PMID: 29559344 Free article. Clinical Trial.
Differential Changes in Inflammatory Mononuclear Phagocyte and T-Cell Profiles within Psoriatic Skin during Treatment with Guselkumab vs. Secukinumab.
Mehta H, Mashiko S, Angsana J, Rubio M, Hsieh YM, Maari C, Reich K, Blauvelt A, Bissonnette R, Muñoz-Elías EJ, Sarfati M. Mehta H, et al. Among authors: munoz elias ej. J Invest Dermatol. 2021 Jul;141(7):1707-1718.e9. doi: 10.1016/j.jid.2021.01.005. Epub 2021 Jan 30. J Invest Dermatol. 2021. PMID: 33524368 Free article. Clinical Trial.
Inflammatory Skin Disorders: Monocyte-Derived Cells Take Center Stage.
Mehta H, Angsana J, Bissonnette R, Muñoz-Elías EJ, Sarfati M. Mehta H, et al. Among authors: munoz elias ej. Front Immunol. 2021 Jul 14;12:691806. doi: 10.3389/fimmu.2021.691806. eCollection 2021. Front Immunol. 2021. PMID: 34335599 Free PMC article. Review. No abstract available.
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