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Mechanisms of Modulation of Mitochondrial Architecture.
Muñoz JP, Basei FL, Rojas ML, Galvis D, Zorzano A. Muñoz JP, et al. Biomolecules. 2023 Aug 7;13(8):1225. doi: 10.3390/biom13081225. Biomolecules. 2023. PMID: 37627290 Free PMC article. Review.
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress.
Bravo R, Vicencio JM, Parra V, Troncoso R, Munoz JP, Bui M, Quiroga C, Rodriguez AE, Verdejo HE, Ferreira J, Iglewski M, Chiong M, Simmen T, Zorzano A, Hill JA, Rothermel BA, Szabadkai G, Lavandero S. Bravo R, et al. Among authors: munoz jp. J Cell Sci. 2011 Jul 1;124(Pt 13):2143-52. doi: 10.1242/jcs.080762. Epub 2011 May 31. J Cell Sci. 2011. PMID: 21628424 Free PMC article.
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Sebastián D, Hernández-Alvarez MI, Segalés J, Sorianello E, Muñoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, Orešič M, Pich S, Burcelin R, Palacín M, Zorzano A. Sebastián D, et al. Among authors: munoz jp. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5523-8. doi: 10.1073/pnas.1108220109. Epub 2012 Mar 16. Proc Natl Acad Sci U S A. 2012. PMID: 22427360 Free PMC article.
Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Muñoz JP, Ivanova S, Sánchez-Wandelmer J, Martínez-Cristóbal P, Noguera E, Sancho A, Díaz-Ramos A, Hernández-Alvarez MI, Sebastián D, Mauvezin C, Palacín M, Zorzano A. Muñoz JP, et al. EMBO J. 2013 Aug 28;32(17):2348-61. doi: 10.1038/emboj.2013.168. Epub 2013 Aug 6. EMBO J. 2013. PMID: 23921556 Free PMC article.
A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells.
Segalés J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A. Segalés J, et al. Among authors: munoz jp. Am J Physiol Endocrinol Metab. 2013 Nov 15;305(10):E1208-21. doi: 10.1152/ajpendo.00546.2012. Epub 2013 Aug 13. Am J Physiol Endocrinol Metab. 2013. PMID: 23941871 Free article.
Mfn2 modulates the unfolded protein response.
Muñoz JP, Zorzano A. Muñoz JP, et al. Cell Cycle. 2014;13(4):491-2. doi: 10.4161/cc.27782. Epub 2014 Jan 13. Cell Cycle. 2014. PMID: 24419149 No abstract available.
118 results