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p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Solé L, Lobo-Jarne T, Álvarez-Villanueva D, Alonso-Marañón J, Guillén Y, Guix M, Sangrador I, Rozalén C, Vert A, Barbachano A, Lop J, Salido M, Bellosillo B, García-Romero R, Garrido M, González J, Martínez-Iniesta M, López-Arribillaga E, Salazar R, Montagut C, Torres F, Iglesias M, Celià-Terrassa T, Muñoz A, Villanueva A, Bigas A, Espinosa L. Solé L, et al. Among authors: munoz a. Nat Commun. 2022 May 23;13(1):2866. doi: 10.1038/s41467-022-30382-9. Nat Commun. 2022. PMID: 35606354 Free PMC article.
The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.
Aguilera O, Peña C, García JM, Larriba MJ, Ordóñez-Morán P, Navarro D, Barbáchano A, López de Silanes I, Ballestar E, Fraga MF, Esteller M, Gamallo C, Bonilla F, González-Sancho JM, Muñoz A. Aguilera O, et al. Among authors: munoz a. Carcinogenesis. 2007 Sep;28(9):1877-84. doi: 10.1093/carcin/bgm094. Epub 2007 Apr 21. Carcinogenesis. 2007. PMID: 17449905
SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity.
Barbáchano A, Ordóñez-Morán P, García JM, Sánchez A, Pereira F, Larriba MJ, Martínez N, Hernández J, Landolfi S, Bonilla F, Pálmer HG, Rojas JM, Muñoz A. Barbáchano A, et al. Among authors: munoz a. Oncogene. 2010 Aug 26;29(34):4800-13. doi: 10.1038/onc.2010.225. Epub 2010 Jun 14. Oncogene. 2010. PMID: 20543868 Free article.
Vitamin D has wide regulatory effects on histone demethylase genes.
Pereira F, Barbáchano A, Singh PK, Campbell MJ, Muñoz A, Larriba MJ. Pereira F, et al. Among authors: munoz a. Cell Cycle. 2012 Mar 15;11(6):1081-9. doi: 10.4161/cc.11.6.19508. Epub 2012 Mar 15. Cell Cycle. 2012. PMID: 22370479 Free article.
Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.
Aguilera Ó, González-Sancho JM, Zazo S, Rincón R, Fernández AF, Tapia O, Canals F, Morte B, Calvanese V, Orgaz JL, Niell N, Aguilar S, Freije JM, Graña O, Pisano DG, Borrero A, Martínez-Useros J, Jiménez B, Fraga MF, García-Foncillas J, López-Otín C, Lafarga M, Rojo F, Muñoz A. Aguilera Ó, et al. Among authors: munoz a. Oncotarget. 2015 Mar 20;6(8):5903-17. doi: 10.18632/oncotarget.3464. Oncotarget. 2015. PMID: 25788273 Free PMC article.
SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.
Barbáchano A, Fernández-Barral A, Pereira F, Segura MF, Ordóñez-Morán P, Carrillo-de Santa Pau E, González-Sancho JM, Hanniford D, Martínez N, Costales-Carrera A, Real FX, Pálmer HG, Rojas JM, Hernando E, Muñoz A. Barbáchano A, et al. Among authors: munoz a. Oncogene. 2016 Jun 9;35(23):2991-3003. doi: 10.1038/onc.2015.366. Epub 2015 Oct 12. Oncogene. 2016. PMID: 26455323 Free article.
2,577 results