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Novel thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones.
Benova A, Ferencakova M, Bardova K, Funda J, Prochazka J, Spoutil F, Cajka T, Dzubanova M, Balcaen T, Kerckhofs G, Willekens W, van Lenthe GH, Alquicer G, Pecinova A, Mracek T, Horakova O, Rossmeisl M, Kopecky J, Tencerova M. Benova A, et al. Among authors: mracek t. Mol Metab. 2022 Nov;65:101598. doi: 10.1016/j.molmet.2022.101598. Epub 2022 Sep 11. Mol Metab. 2022. PMID: 36103974 Free PMC article.
Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle.
Janovska P, Zouhar P, Bardova K, Otahal J, Vrbacky M, Mracek T, Adamcova K, Lenkova L, Funda J, Cajka T, Drahota Z, Stanic S, Rustan AC, Horakova O, Houstek J, Rossmeisl M, Kopecky J. Janovska P, et al. Among authors: mracek t. Mol Metab. 2023 Mar;69:101683. doi: 10.1016/j.molmet.2023.101683. Epub 2023 Jan 30. Mol Metab. 2023. PMID: 36720306 Free PMC article.
Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity.
Benova A, Ferencakova M, Bardova K, Funda J, Prochazka J, Spoutil F, Cajka T, Dzubanova M, Balcaen T, Kerckhofs G, Willekens W, van Lenthe GH, Charyyeva A, Alquicer G, Pecinova A, Mracek T, Horakova O, Coupeau R, Hansen MS, Rossmeisl M, Kopecky J, Tencerova M. Benova A, et al. Among authors: mracek t. Commun Biol. 2023 Oct 14;6(1):1043. doi: 10.1038/s42003-023-05407-8. Commun Biol. 2023. PMID: 37833362 Free PMC article.
Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity.
Pravenec M, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Trnovská J, Škop V, Marková I, Malínská H, Hüttl M, Kazdová L, Bardová K, Tauchmannová K, Vrbacký M, Nůsková H, Mráček T, Kopecký J, Houštěk J. Pravenec M, et al. Among authors: mracek t. Physiol Res. 2017 Dec 20;66(6):917-924. doi: 10.33549/physiolres.933811. Physiol Res. 2017. PMID: 29261326 Free article.
Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase.
Hlozkova K, Pecinova A, Alquezar-Artieda N, Pajuelo-Reguera D, Simcikova M, Hovorkova L, Rejlova K, Zaliova M, Mracek T, Kolenova A, Stary J, Trka J, Starkova J. Hlozkova K, et al. Among authors: mracek t. BMC Cancer. 2020 Jun 5;20(1):526. doi: 10.1186/s12885-020-07020-y. BMC Cancer. 2020. PMID: 32503472 Free PMC article.
Mitochondrial respiration supports autophagy to provide stress resistance during quiescence.
Magalhaes-Novais S, Blecha J, Naraine R, Mikesova J, Abaffy P, Pecinova A, Milosevic M, Bohuslavova R, Prochazka J, Khan S, Novotna E, Sindelka R, Machan R, Dewerchin M, Vlcak E, Kalucka J, Stemberkova Hubackova S, Benda A, Goveia J, Mracek T, Barinka C, Carmeliet P, Neuzil J, Rohlenova K, Rohlena J. Magalhaes-Novais S, et al. Among authors: mracek t. Autophagy. 2022 Oct;18(10):2409-2426. doi: 10.1080/15548627.2022.2038898. Epub 2022 Mar 8. Autophagy. 2022. PMID: 35258392 Free PMC article.
65 results